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It is 4S study. 4444 patients with known cardiovascular diseases were randomized either to simvastatin or to placebo. 202 were known with diabetes.

Among non-diabetic subjects it was 25% benefit in the simvastatin treated group. Among the diabetic patients however it was greater benefit of blood pressure lowering such as in simvastatin group 55% lower incidence of events than those randomized for placebo.