In a population of people 50 or 60 years old, about 30% are harboring these adenomatous polyps. Now the issue is that only a small percentage of them will evolve into cancer. So fundamentally, when we approach screening from a polyp perspective, we start detecting all these polyps, removing them and following people for development of recurrent polyps. This requires us to spend a lot of time, energy and money doing things that probably, in many cases, would never really evolve into a problem. But as for right now, all we know is to deal with adenomas and to take them out.