front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |review

Hibernation, persistent myocardial dysfunction, describes poorly functioning regions of chronically undeperfused myocardium that can regain the ability to contract when flow is re-established by CABG.The recovery time of hibernating myocardium after revascularisation has been variable. Immediate recovery if function might indicate that hibernation was acute, slow recovery over days to weeks might suggest sub acute hibernation, and recovery (month to years) might suggest that the hibernation was chronic. Recovery time could be dependent on a number of factors, including duration of ischemia, severity of ischemia, degree of revascularisation (complete versus partial), and amount of myocyte dedifferentiation within the hibernating zone. Recovery that occurs over days to weeks after revascularisation of a hibernating segment might represent stunning. Recovery that occurs over a longer time period might represent the regeneration of myofibrils and repair of structural alterations that occur4ed during the chronic hibernating phase.