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A: constriction of visial field, B: impairment of hearing, C: disturbance of sensation, D: ataxia, E: extrapyramidal symptoms, F: exaggerated tendon reflex, F: weak tendon refex, H: pathological reflexes, I: slight mental disturbance

(Data from Tsubaki, 1965)

Methylmercury poisoning exhibits a variety of neuropathological features from severe changes at the early stage to mild changes. In the adult and infant type, predilection sites of the changes are clear; calcarine, post-central, pre-central, and superior temporal cortices are most vulnerable, whereas the changes in the brains of fetal type are less-localized, and show hypoplasia or developmental arrest, rather than neuronal destruction.