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Hurricane Mitch and Hurricane Georges were among the most severe and powerful storms ever to hit Central America and the Caribbean in the history of the hemisphere. Hurricane Mitch, carrying 180-mph winds at its height on October 26 and 27, l998, produced massive flooding and destruction, engulfing entire villages and destroying homes, crops and infrastructure. The face of these countries was permanently changed by the devastation.

Moreover, in most countries of this region the public health infrastructure has deteriorated. Limited financial and human resources and competing priorities have resulted in a "crisis mentality" with emphasis on implementing so-called emergency control methods in response to epidemics rather than on developing programs to prevent epidemic transmission. This approach has been particularly detrimental to dengue control because, in most countries, surveillance is (just as in the U.S.) very inadequate; the system to detect increased transmission normally relies on reports by local physicians who often do not consider dengue in their differential diagnoses. As a result, an epidemic has often reached or passed transmission before it is detected