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- This graph shows the smallest absolute risk
reduction detectable in trials of a given size - On the horizontal axis is the study size (that is, the number of patients randomised in the trial) - And on the vertical axis is the absolute risk reduction that would be detectable - So, for example, suppose after head injury 20% of patients were dead. For a study to detect a 10% absolute risk reduction, that is from 20% dead to 10% dead, we would need a study with about 400 patients |