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Nondiabetic obese women (n=14) were placed on a very low calorie diet (mean energy intake 3.9 0.1 MJ/d [941 27 kcal/d], 20% from fat) for 21 days. BMI was reduced by a mean of 2.1 kg/m2, and adipose tissue mass was reduced by a mean of 3 kg. Serum IL-6 concentration was significantly reduced by 17%, but the 32% reduction in CRP was not statistically significant (p=0.14). Tumor necrosis factor " (TNF-") concentration was not changed. 

Reference:
Bastard J-P, Jardel C, Bruckert E, Blondy P, Capeau J, Laville M, Vidal H, Hainque B. Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss. J Clin Endocrinol Metab 2000;85:3338-3342. Web site