Program For Genetics and Psychoses

Principal Investigator: Vishwajit L. Nimgaonkar
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Recent Publications

In 2015

Choudhary M, Kumar A, Tripathi M, Bhatia T, Shivakumar V, Beniwal RP, Gur RC, Gur RE, Nimgaonkar VL, Deshpande SN. (2015). F-18 fluorodeoxyglucose positron emission tomography study of impaired emotion processing in first episode schizophrenia. Schizophrenia Research. 2015 Mar;162(1-3):103-7. doi: 10.1016/j.schres.2015.01.028. PMID: 25655909.

Chakraborty S, Thomas P, Bhatia T, Nimgaonkar VL, Deshpande SN (2015). Assessment of severity of autism using the Indian scale for assessment of autism. Indian J Psychol Med. 2015 Apr-Jun;37(2):169-74. doi: 10.4103/0253-7176.155616. PMID: 25969602.

Narayanan SS, Bhatia T, Velligan DI, Nimgaonkar VL, Deshpande SN (2015). A case control study of association between cognition and functional capacity in schizophrenia. Schizophr Res. 2015 Oct 30. pii: S0920-9964(15)30025-6. doi: 10.1016/j.schres.2015.10.025. [Epub ahead of print]. PMID: 26527248.

Seleem M, Merranko J, Goldstein T, Goldstein B, Axelson D, Brent D, Nimgaonkar VL, Diler R Sakolsky D, Kupfer D, Birmaher B. The Longitudinal Course of Sleep Timing and Circadian Preferences in Adults with Bipolar Disorder. Bipolar Disorders. 2014 Dec 19. doi: 10.1111/bdi.12286. [Epub ahead of print]

Mansour H, Tobar S, Fathi W, Ibrahim I, Wood J, Elassy M, Elsayed H, Yassin A, Salah H, Eissa A, El-Boraie H, El-Boraie O, Dobea A, Osama H, Gomaa Z, El-Bahaei W, Monk TH, Nimgaonkar VL (2015). Arabic versions of the sleep timing questionnaire and the composite scale of morningness. Asian J Psychiatry, 13:48-51. doi: 10.1016/j.ajp.2014.10.004. Epub 2014 Oct 29. PMID: 25466780.

D'Aiuto L, Zhi Y, Das D, Wilcox M, Johnson J, McClain L, MacDonald M, Di Maio R, Schurdak ME, Piazza P, Viggiano L, Sweet R, Kinchington P, Ghosh Bhattacharjee A, Yolken R, Nimgaonkar VL (2015). Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation. Organogenesis. 10(4):365-77. doi: 10.1080/15476278.2015.1011921.

Ibrahim I, Tobar S, Elassy M, Mansour H, Chen K, Wood J, Gur RC, Gur RE, El Bahaei W, Nimgaonkar VL (2015). Practice effects distort translational validity estimates for a Neurocognitive Battery. Journal of Clinical and Experimental Neuropsychology. 37(5):530-7. doi: 10.1080/13803395.2015.1037253. Epub 2015 Jun 9. PMID: 26054545.

Das DK, Tapias V, D’Aiuto L, Chowdari KV, Francis L, Zhi Y, Ghosh A, Surti U, Tischfield J, Sheldon M, Moore JC, Fish K, Nimgaonkar VL (2015). Genetic and morphological features of human iPSC-derived neurons with chromosome 15q11.2 (BP1-BP2) deletions. Molecular Neuropsychiatry. 1:116-123 (DOI:10.1159/000430916). PMID: 26528485.

McClain L, Zhi Y, Cheng HH; Ghosh A, Piazza P, Yee MB, Kumar S, Milosevic J, Bloom DC, Arav-Boger R, Kinchington PR, Yolken RH, Nimgaonkar VL, D’Aiuto L (2015). Broad-spectrum non-nucleoside inhibitors of human herpesviruses. Antiviral Research. 121: 16–23. PMID: 26079681.

Ravindranath V, Dang HM, Goya RG, Mansour H, Nimgaonkar VL, Russell VA, Xin Y. (2015) Regional research priorities in brain and nervous system disorders. Nature. 527(7578):S198-206. doi: 10.1038/nature16036. PMID: 26580328.

Kos MZ, Carless MA, Peralta J, Blackburn A, Almeida M, Roalf D, Pogue-Geile MF, Prasad K, Gur RC, Nimgaonkar V, Curran JE, Duggirala R, Glahn DC, Blangero J, Gur RE, Almasy L. (2015). Exome Sequence Data From Multigenerational Families Implicate AMPA Receptor Trafficking in Neurocognitive Impairment and Schizophrenia Risk. Schizophr Bull. 2015 Sep 24. pii: sbv135. [Epub ahead of print]. PMID: 26405221.

Prasad KM, Upton CH, Nimgaonkar VL, Keshavan MS. (2015). Differential susceptibility of white matter tracts to inflammatory mediators in schizophrenia: an integrated DTI study. Schizophr Res. 2015 Jan;161(1):119-25. doi: 10.1016/j.schres.2014.09.043. Epub 2014 Oct 22. PMID: 25449712.

Nimgaonkar VL, Yolken RH, Wang T, Chang CH, McClain L, McDade E, Snitz B, Ganguli M (In press). Temporal cognitive decline associated with exposure to infectious agents in a population-based, aging cohort. Journal of Alzheimer Disease and Associated Disorders.

McNulty J, D’Aiuto L, Zhi Y, McClain L, Zepeda-Velázquez C, Ler S, Yee M, Piazza P, Yolken RH, Kinchington PR, Nimgaonkar VL (in press). Asymmetric synthesis of Amaryllidacea alkaloid trans-dihydrolycoricidine discloses potent effects against herpesvirus infections. American Chemical Society Medicinal Chemistry Letters.

Watson AM, Pribadi M, Chowdari KV, Clifton S, Wood J; Miller B, Coppola G, Nimgaonkar VL (in press). C9orf72 repeat expansions that cause frontotemporal dementia are detectable among patients with psychosis. Psychiatry Research.

Before 2015, selected

Bhatia T, Mazumdar S, Mishra NN, Gur RE, Gur RC, Nimgaonkar VL, Deshpande SN. Protocol to evaluate the impact of yoga supplementation on cognitive function in schizophrenia: a randomised controlled trial. Acta europsychiatr. 2014 Oct;26(5):280-90. PubMed PMID: 25241756.

Narendran R, Lopresti BJ, Mason NS, Deuitch L, Paris J, Himes ML, Kodavali CV,Nimgaonkar VL. Cocaine abuse in humans is not associated with increased microglial activation: an 18-kDa translocator protein positron emission tomography imaging study with [11C]PBR28. J Neurosci. 2014 Jul 23;34(30):9945-50. PubMed PMID: 25057196.

Frank E, Nimgaonkar VL, Phillips ML, Kupfer DJ. All the world's a (clinical)stage: rethinking bipolar disorder from a longitudinal perspective. Mol Psychiatry. 2014 Jul 22. [Epub ahead of print] PubMed PMID: 25048003.

Roalf DR, Vandekar SN, Almasy L, Ruparel K, Satterthwaite TD, Elliott MA, Podell J, Gallagher S, Jackson CT, Prasad K, Wood J, Pogue-Geile MF, Nimgaonkar VL, Gur RC, Gur RE. Heritability of Subcortical and Limbic Brain Volume and Shape in Multiplex-Multigenerational Families with Schizophrenia. Biol Psychiatry. 2014 May 28. [Epub ahead of print] PubMed PMID: 24976379.

Sewilam AM, Watson AM, Kassem AM, Clifton S, McDonald MC, Lipski R, Deshpande S, Mansour H, Nimgaonkar VL. Suggested avenues to reduce the stigma of mental illness in the Middle East. Int J Soc Psychiatry. 2014 Jun 23. [Epub ahead of print] PubMed PMID: 24957595.

Mishra NN, Bhatia T, Kumar N, Nimgaonkar VL, Parker LS, Deshpande SN. Knowledge & attitudes of mental health professionals regarding psychiatric research. Indian J Med Res. 2014 Feb;139:246-51. PubMed PMID: 24718399.

D'Aiuto L, Prasad KM, Upton CH, Viggiano L, Milosevic J, Raimondi G, McClain L, Chowdari K, Tischfield J, Sheldon M, Moore JC, Yolken RH, Kinchington PR,Nimgaonkar VL. Persistent Infection by HSV-1 Is Associated With Changes in Functional Architecture of iPSC-Derived Neurons and Brain Activation Patterns Underlying Working Memory Performance. Schizophr Bull. 2014 Mar 12. [Epub ahead of print] PubMed PMID: 24622295.

Thakral S, Bhatia T, Gettig EA, Nimgaonkar VL, Deshpande SN. A comparative study of health locus of control in patients with schizophrenia and their first degree relatives. Asian J Psychiatr. 2014 Feb;7(1):34-7. PubMed PMID: 24524707.

Roalf DR, Ruparel K, Gur RE, Bilker W, Gerraty R, Elliott MA, Gallagher RS, Almasy L, Pogue-Geile MF, Prasad K, Wood J, Nimgaonkar VL, Gur RC. Neuroimaging predictors of cognitive performance across a standardized neurocognitive battery. Neuropsychology. 2014 Mar;28(2):161-76. PubMed PMID: 24364396.

Bhatia T, Agrawal A, Beniwal RP, Thomas P, Monk TH, Nimgaonkar VL, Deshpande SN. A Hindi version of the Composite Scale of Morningness. Asian J Psychiatr. 2013 Dec;6(6):581-4. PubMed PMID: 24309877.

De S, Bhatia T, Thomas P, Chakraborty S, Prasad S, Nagpal R, Nimgaonkar VL,Deshpande SN. Bizarre delusions: a qualitative study on Indian schizophrenia patients. Indian J Psychol Med. 2013 Jul;35(3):268-72. PubMed PMID: 24249929.

Kodavali CV, Watson AM, Prasad KM, Celik C, Mansour H, Yolken RH, Nimgaonkar VL. HLA associations in schizophrenia: are we re-discovering the wheel? Am J Med Genet B Neuropsychiatr Genet. 2014 Jan;165B(1):19-27. Review. PubMed PMID: 24142843.

Kukshal P, Kodavali VC, Srivastava V, Wood J, McClain L, Bhatia T, Bhagwat AM, Deshpande SN, Nimgaonkar VL, Thelma BK. Dopaminergic gene polymorphisms and cognitive function in a north Indian schizophrenia cohort. J Psychiatr Res. 2013 Nov;47(11):1615-22. PubMed PMID: 23932573.

Mishra NN, Bhatia T, Parker LS, Nimgaonkar VL, Deshpande SN. Tutorials on basics of bioethics: an experience with post-graduate health professionals. Stud Health Technol Inform. 2013;192:1054. PubMed PMID: 23920828.

Thomas P, Bhatia T, Gauba D, Wood J, Long C, Prasad K, Dickerson FB, Gur RE, Gur RC, Yolken RH, Nimgaonkar VL, Deshpande SN. Exposure to herpes simplex virus,type 1 and reduced cognitive function. J Psychiatr Res. 2013 Nov;47(11):1680-5. PubMed PMID: 23920011.

Gulsuner S, Walsh T, Watts AC, Lee MK, Thornton AM, Casadei S, Rippey C, Shahin H; Consortium on the Genetics of Schizophrenia (COGS); PAARTNERS Study Group, Nimgaonkar VL, Go RC, Savage RM, Swerdlow NR, Gur RE, Braff DL, King MC,McClellan JM. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell. 2013 Aug 1;154(3):518-29. PubMed PMID: 23911319.

Bamne MN, Ponder CA, Wood JA, Mansour H, Frank E, Kupfer DJ, Young MW, Nimgaonkar VL. Application of an ex vivo cellular model of circadian variation for bipolar disorder research: a proof of concept study. Bipolar Disord. 2013 Sep;15(6):694-700. PubMed PMID:23782472.

Kukshal P, Bhatia T, Bhagwat AM, Gur RE, Gur RC, Deshpande SN, Nimgaonkar VL,Thelma BK. Association study of neuregulin-1 gene polymorphisms in a North Indian schizophrenia sample. Schizophr Res. 2013 Mar;144(1-3):24-30. PubMed PMID: 23360725.

Nimgaonkar VL, Yolken RH. Neurotropic infectious agents and cognitive impairment in schizophrenia. Schizophr Bull. 2012 Nov;38(6):1135-6. PubMed PMID: 23117985.