Department of Environmental and Occupational Health

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Valerian E. Kagan - Publications

Peer-Reviewed Papers in the US and International Journals (last 5 years)

  1. Godoy LC, Muñoz-Pinedo C, Castro L, Cardaci S, Schonhoff CM, King M, Tórtora V, Marín M, Miao Q, Jiang JF, Kapralov A, Jemmerson R, Silkstone GG, Patel JN, Evans JE, Wilson MT, Green DR, Kagan VE, Radi R, Mannick JB.  Disruption of the M80-Fe Ligation Stimulates the Translocation of Cytochrome C to the Cytoplasm and Nucleus in Nonapoptotic Cells.  Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2653-8. Epub 2009 Feb 5.  PMID: 19196960

  2. Konduru NV, Tyurina YY, Feng W, Basova LV, Belikova NA, Bayir H, Clark K, Rubin M, Stolz D, Vallhov H, Scheynius A, Witasp E, Fadeel B, Kichambare PD, Star A, Kisin ER, Murray AR, Shvedova AA, Kagan VE. Phosphatidylserine Targets Single-walled Carbon Nanotubes to Professional Phagocytes in Vitro and in Vivo.  PLoS ONE. 2009;4(2):e4398. Epub 2009 Feb 9. PMID: 19198650

  3. Shurin MR, Potapovich AI, Tyurina YY, Tourkova IL, Shurin GV, Kagan VE.  Recognition of Live Phosphatidylserine-Labeled Tumor Cells by Dendritic Cells: A Novel Approach to Immunotherapy of Skin Cancer.  Cancer Res. 2009 Mar 10. PMID: 19276376

  4. Kagan VE, Bayır HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA, Borisenko G.  Cytochrome C/Cardiolipin Relations in Mitochondria: A Kiss of Death.  Free Radic Biol Med. 2009 Mar 11. PMID: 19285551

  5. Murray AR, Kisin E, Leonard SS, Young SH, Kommineni C, Kagan VE, Castranova V, Shvedova AA.  Oxidative Stress and Inflammatory Response in Dermal Toxicity of Single-walled Carbon Nanotubes.  Toxicology. 2009 Mar 29;257(3):161-71. Epub 2008 Dec 30.  PMID: 19150385

  6. Vladimirov VA, Proskurnia EV, Demin EM, Matveeva NS, Lubitskiy OB, Novikov AA, Izmailov DY, Osipov AN, Tikonov VP, Kagan VE.  Dihydroquercetin (taxifolin) and other flavonoids as inhibitors of free radical formation at key stages of apoptosis.  Biochemistry (Mosc), 74(3): 301-7, 2009. PMID: 19364325

  7. Belikova NA, Jiang J, Stoyanovsky DA, Glumac A, Bayir H, Greenberger JS, Kagan VE. Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO* and protects mouse embryonic cells against irradiation-induced apoptosis. FEBS Lett. 2009 May 7. PMID: 19427865

  8. Belikova NA, Tyurina YY, Borisenko G, Tyurin V, Samhan Arias AK, Yanamala N, Furtmüller PG, Klein-Seetharaman J, Obinger C, Kagan VE. Heterolytic reduction of fatty acid hydroperoxides by cytochrome c/cardiolipin complexes: antioxidant function in mitochondria. J Am Chem Soc. 2009 Aug 19;131(32):11288-9. PMID: 19627079

  9. Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, Bayır H. Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions. Adv Drug Deliv Rev. 2009 Aug 27. PMID: 19716396

  10. Jiang J, McDonald PR, Dixon TM, Franicola D, Zhang X, Nie S, Epperly LD, Huang Z, Kagan VE, Lazo JS, Epperly MW, Greenberger JS.  Synthetic protection short interfering RNA screen reveals glyburide as a novel radioprotector.  Radiat Res. 2009 Oct;172(4):414-22.  PMID: 19772462

  11. Rajagopalan MS, Gupta K, Epperly MW, Franicola D, Zhang X, Wang H, Zhao H, Tyurin VA, Pierce JG, Kagan VE, Wipf P, Kanai AJ, Greenberger JS. The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair. In Vivo. 2009 Sep-Oct;23(5):717-26. PMID: 19779106

  12. Tyurina YY, Tyurin VA, Kapralova VI, Amoscato AA, Epperly MW, Greenberger JS, Kagan VE. Mass-spectrometric characterization of phospholipids and their hydroperoxide derivatives in vivo: effects of total body irradiation. Methods Mol Biol. 2009;580:153-83. PMID: 19784599

  13. Belikova NA, Glumac A, Rafikov R, Jiang J, Greenberger JS, Kagan VE, Bayir H. Radioprotection by short-term oxidative preconditioning: Role of manganese superoxide dismutase.  FEBS Lett. 2009 Oct 13. PMID: 19822147.

  14. Sengupta R, Billiar TR, Atkins JL, Kagan VE, Stoyanovsky DA. Nitric oxide and dihydrolipoic acid modulate the activity of caspase 3 in HepG2 cells. FEBS Lett. 2009 Nov 3;583(21):3525-30. Epub 2009 Oct 12. PMID: 19822150

  15. Allen BL, Kotchey GP, Chen Y, Yanamala NV, Klein-Seetharaman J, Kagan VE, Star A. Mechanistic investigations of horseradish peroxidase-catalyzed degradation of single-walled carbon nanotubes. J Am Chem Soc. 2009 Dec 2;131(47):17194-205. PMID: 19891488

  16. Jiang, J, Stoyanovsky DA, Belikova NA, Tyurina YY, Zhao Q, Tungekar MA, Kapralova V, Huang Z, Mintz AH, Greenberger JS, Kagan VE. A Mitochondria-Targeted Triphenylphosphonium-Conjugated Nitroxide Functions as a Radioprotector/Mitigator. Radiat. Res. 2009 Dec; 172(6): 706-717. PMID: 19929417

  17. Tyurin VA, Tyurina YY, Ritov VB, Lysytsya A, Amoscato AA, Kochanek PM, Hamilton R, Dekosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues. Methods Mol Biol. 2010;610:353-74. PubMed PMID: 20013189

  18. Sengupta R, Billiar TR, Kagan VE, Stoyanovsky DA. Nitric oxide and thioredoxin type 1 modulate the activity of caspase 8 in HepG2 cells. Biochem Biophys Res Commun. 2010 Jan 1;391(1):1127-30. Epub 2009 Dec 11. PMID: 20005201

  19. Hilmi IA, Peng Z, Planinsic RM, Damian D, Dai F, Tyurina YY, Kagan VE, Kellum JA. N-acetylcysteine does not prevent hepatorenal ischaemia-reperfusion injury in patients undergoing orthotopic liver transplantation. Nephrol Dial Transplant. 2010 Feb 22. PMID: 20179007

  20. Kagan VE, Konduru NV, Feng W, Allen BL, Conroy J, Volkov Y, Vlasova II, Belikova NA, Yanamala N, Kapralov A, Tyurina YY, Shi J, Kisin ER, Murray AR, Franks J, Stolz D, Gou P, Klein-Seetharaman J, Fadeel B, Star A, Shvedova AA. Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. Nat Nanotechnol. 2010 Apr 4. PMID: 20364135

  21. Li W, Wu S, Ahmad M, Jiang J, Liu H, Nagayama T, Rose ME, Tyurin VA, Tyurina YY, Borisenko GG, Belikova N, Chen J, Kagan VE, Graham SH. The Cyclooxygenase Site, But Not the Peroxidase Site of Cyclooxygenase-2 is required for Neurotoxicity in Hypoxic and Ischemic Injury. J Neurochem, 2010

  22. Shvedova AA, Kagan VE. The role of Nanotoxicology in realizing the Ďhelping without harmí paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes. J Intern Med, 267(1):106-18, 2010

  23. Shvedova AA, Kagan VE, Fadeel B. Close encounters of the small kind: adverse effects of man-made materials interfacing with the nano-cosmos of biological systems. Annu Rev Pharmacol Toxicol. 20:63-88, 2010, Review

  24. Stoyanovsky DA, Kapralov A, Huang Z, Maeda A, Osipov A, Hsia CJ, Ma L, Kochanek PM, Bayir H, Kagan VE. Unusual Peroxidase Activity of Polynitroxylated Pegylated Hemoglobin: Elimination of H2O2 Coupled with Intramolecular Oxidation of Nitroxides. Biochem Biophys Res Commun. 2010 Jul 16. PMID: 20643098

  25. Kagan VE, Shi J, Feng W, Shvedova AA, Fadeel B. Fantastic voyage and opportunities of engineered nanomaterials: What are the potential risks of occupational exposures? J Occup Environ Med. 2010 Sep;52(9):943-946. PubMed PMID: 20829674

  26. Huang Z, Jiang J, Belikova NA, Stoyanovsky DA, Kagan VE, Mintz AH. Protection of normal brain cells from γ-irradiation-induced apoptosis by a mitochondria-targeted triphenyl-phosphonium-nitroxide: a possible utility in glioblastoma therapy. J Neurooncol. 2010 Oct;100(1):1-8. Epub 2010 Sep 12. PubMed PMID: 20835910

  27. Walson KH, Tang M, Glumac A, Alexander H, Manole MD, Ma L, Hsia CJ, Clark RS, Kochanek PM, Kagan VE, Bayir H. Normoxic versus hyperoxic resuscitation in pediatric asphyxial cardiac arrest: Effects on oxidative stress. Crit Care Med. 2010 Nov 4. PubMed PMID: 21057313

  28. Vlasova II, Feng WH, Goff JP, Giorgianni A, Do D, Gollin SM, Lewis DW, Kagan VE, Yalowich JC. Myeloperoxidase-dependent oxidation of etoposide in human myeloid progenitor CD34+ cells. Mol Pharmacol. 2011 Mar;79(3):479-87. Epub 2010 Nov 19. PubMed PMID: 21097707; PubMed Central PMCID: PMC3061368

  29. Li HH, Xu J, Wasserloos KJ, Li J, Tyurina YY, Kagan VE, Wang X, Chen AF, Liu ZQ, Stoyanovsky D, Pitt BR, Zhang LM. Cytoprotective effects of Albumin, Nitrosated or Reduced, in Cultured Rat Pulmonary Vascular Cells. Am J Physiol Lung Cell Mol Physiol. 2011 Jan 14. PMID: 21239532

  30. Thambiayya K, Wasserloos KJ, Huang Z, Kagan VE, St Croix CM, Pitt BR. LPS-induced decrease in intracellular labile zinc [Zni] contributes to apoptosis in cultured sheep pulmonary artery endothelial cells (SPAEC). Am J Physiol Lung Cell Mol Physiol. 2011 Jan 14. PMID: 21239534

  31. Samhan-Arias AK, Tyurina YY, Kagan VE. Lipid antioxidants: free radical scavenging versus regulation of enzymatic lipid peroxidation. J Clin Biochem Nutr. 2011 Jan;48(1):91-5. Epub 2010 Dec 28. PubMed PMID: 21297919

  32. Tyurina YY, Tyurin VA, Kapralova VI, Wasserloos K, Mosher M, Epperly MW, Greenberger JS, Pitt BR, Kagan VE. Oxidative lipidomics of ϒ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Radiat Res. 2011 May;175(5):610-21. Epub 2011 Feb 21. PMID:21338246

  33. Kapralov AA, Yanamala N, Tyurina YY, Castro L, Arias AS, Vladimirov YA, Maeda A, Weitz AA, Peterson J, Mylnikov D, Demicheli V, Tortora V, Klein-Seetharaman J, Radi R, Kagan VE. Topography of tyrosine residues and their involvement in peroxidation of polyunsaturated cardiolipin in cytochrome c/cardiolipin peroxidase complexes. Biochim Biophys Acta. 2011 Sep;1808(9):2147-55. Epub 2011 Apr 29. PubMed PMID: 21550335

  34. Stoyanovsky, D. A., Maeda, A., Atkins, J. L., and Kagan, V. E. (2011) Assessments of Thiyl Radicals in Biosystems: Difficulties and New Applications, Anal Chem. 2011 Jun 1. PMID:21591751

  35. Jiang J, Maeda A, Ji J, Baty CJ, Watkins SC, Greenberger JS, Kagan VE. Are mitochondrial reactive oxygen species required for autophagy? Biochem Biophys Res Commun. 2011 Aug 19;412(1):55-60. Epub 2011 Jul 22. PubMed PMID: 21806968

  36. Belikova NA, Glumac AL, Kapralova V, Cheikhi A, Tyurina YY, Vagni VA, Kochanek PM, Kagan VE, BayÓr H. A high-throughput screening assay of ascorbate in brain samples. J Neurosci Methods. 2011 Aug 9. PubMed PMID: 21855575

  37. Tyurin VA, Cao W, Tyurina YY, Gabrilovich DI, Kagan VE. Mass-spectrometric characterization of peroxidized and hydrolyzed lipids in plasma and dendritic cells of tumor-bearing animals. Biochem Biophys Res Commun. 2011 Sep 16;413(1):149-53. Epub 2011 Aug 22. PubMed PMID: 21872574

  38. Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, BayÓr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE. A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death. Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499. PubMed PMID: 21988913

  39. Ji J, Tyurina YY, Tang M, Feng W, Stolz DB, Clark RS, Meaney DF, Kochanek PM, Kagan VE, BayÓr H. Mitochondrial Injury after Mechanical Stretch of Cortical Neurons in Vitro: Biomarkers of Apoptosis and Selective Peroxidation of Anionic Phospholipids. J Neurotrauma. 2011 Nov 4. PubMed PMID: 21895519

  40. Tyurina YY, Tungekar MA, Jung MY, Tyurin VA, Greenberger JS, Stoyanovsky DA, Kagan VE. Mitochondria targeting of non-peroxidizable triphenylphosphonium conjugated oleic acid protects mouse embryonic cells against apoptosis: Role of cardiolipin remodeling. FEBS Lett. 2011 Dec 28. PubMed PMID: 22210054

  41. Stoyanovsky DA, Huang Z, Jiang J, Belikova NA, Tyurin V, Epperly MW, Greenberger JS, Bayir H, Kagan VE. A manganese-porphyrin complex decomposes H2O2, inhibits apoptosis, and acts as a radiation mitigator in vivo. ACS Med Chem Lett. 2011 Nov 10;2(11):814-817. PubMed PMID: 22247787

  42. Midwinter RG, Maghzal GJ, Dennis JM, Wu BJ, Cai H, Kapralov AA, Belikova NA, Tyurina YY, Dong LF, Khachigian L, Neuzil J, Kagan VE, Stocker R. Succinobucol induces apoptosis in vascular smooth muscle cells. Free Radic Biol Med. 2012 Mar 1;52(5):871-9. Epub 2011 Dec 21. PMID: 22203369

  43. Samhan-Arias AK, Ji J, Demidova OM, Sparvero LJ, Feng W, Tyurin V, Tyurina YY, Epperly MW, Shvedova AA, Greenberger JS, Bayir H, Kagan VE, Amoscato AA. Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin. Biochim Biophys Acta. 2012 Mar 23. PMID: 22464971

  44. Shi J, Karlsson HL, Johansson K, Gogvadze V, Xiao L, Li J, Burks T, Garcia-Bennett A, Uheida A, Muhammed M, Mathur S, Morgenstern R, Kagan VE, Fadeel B. Microsomal glutathione transferase 1 protects against toxicity induced by silica nanoparticles but not by zinc oxide nanoparticles. ACS Nano. 2012 Mar 27;6(3):1925-38. Epub 2012 Feb 13. PMID:22303956

  45. Kapralov AA, Feng WH, Amoscato AA, Yanamala N, Balasubramanian K, Winnica DE, Kisin ER, Kotchey GP, Gou P, Sparvero LJ, Ray P, Mallampalli RK, Klein-Seetharaman J, Fadeel B, Star A, Shvedova AA, Kagan VE. Selective Adsorption of Surfactant Lipids by Single-Walled Carbon Nanotubes in Mouse Lung upon Pharyngeal Aspiration: Role in Uptake by Macrophages. ACS Nano. 2012 Apr 1. PMID: 22463369

  46. Shvedova AA, Kapralov AA, Feng WH, Kisin ER, Murray AR, Mercer RR, St Croix CM, Lang MA, Watkins SC, Konduru NV, Allen BL, Conroy J, Kotchey GP, Mohamed BM, Meade AD, Volkov Y, Star A, Fadeel B, Kagan VE. Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice. PLoS One. 2012;7(3):e30923. Epub 2012 Mar 30. PMID: 22479306

  47. Shvedova AA, Pietroiusti A, Fadeel B, Kagan VE. Mechanisms of carbon nanotube-induced toxicity: Focus on oxidative stress. Toxicol Appl Pharmacol. 2012 Apr 6. PMID: 22513272

  48. Murray AR, Kisin ER, Tkach AV, Yanamala N, Mercer RR, Young SH, Fadeel B, Kagan VE, Shvedova AA. Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos. Part Fibre Toxicol. 2012 Apr 10;9(1):10. PMID: 22490147

  49. Thambiayya K, Wasserloos KJ, Kagan VE, Stoyanovsky D, Pitt BR. A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis. Am J Physiol Lung Cell Mol Physiol. 2012 Apr 20. PMID: 22523284

  50. Schlattner U, Tokarsaka-Schlattner M, Ramirez S, Tyurina YY, Amoscato AA, Mohammadsanyi D, Huang Z, Jiang J, Yanamala N, Seffouh A, Boissan M, Epand RF, Epand RM, Klein-Seetharaman J, Lacombe ML, Kagan VE.  Dual function of mitochondrial Nm23-H4 in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch. J Biol Chem, 2012 [Epub ahead of print], PMID: 23150663

  51. Tyurin VA, Yanamala N, Tyurina YY, Klein-Seetharaman J, Macphee CH, Kagan VE.  Specificity of Lipoprotein-Associated Phospholipase A(2) toward Oxidized Phosphatidylserine: Lipid Chromatography-Electrospray Ionization Mass Spectrometry Characterization of Products and Computer Modeling of Interactions.  Biochemistry, 2012 [Epub ahead of print], PMID: 23148485

  52. Hoye AT, Davoren JE, Wipf P, Fink MP, Kagan VE.  Correction to targeting mitochondria.  Acc Chem Res, 45(12):2222, 2012, PMID: 23145896

  53. Shvedova AA, Tkach AV, Kisin Er, Khaliullin T, Stanley S, Gutkin DW, Star A, Chen Y, Shurin GV, Shurin MR, Kagan VE.  Carbon Nanotubes Enhance Metastatic Growth of Lung Carcinoma via Up-Regulation of Myeloid-Derived Suppressor Cells.  Small, 2012 [Epub ahead of print], PMID: 22996965

  54. Tyurina YY, Tungekar MA, Jung MY, Tyurin VA, Greenberger JS, Stoyanovsky DA, Kagan VE.  Mitochondria targeting of non-peroxidizable triphenylphosphonium conjugated oleic acid protects mouse embryonic cells against apoptosis: role of cardiolipin remodeling.  FEBS Lett, (3):235-41, 2012, PMID: 22210054

  55. Ji J, Kline AE, Amoscato A, Samhan-Arias AK, Sparvero LJ, Tyurin VA, Tyurina YY, Fink B, Manole MD, Puccio AM, Okonkwo DO, Cheng JP, Alexander H, Clark RS, Kochanek PM, Wipf P, Kagan VE, Bayir H.  Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brian  injury.  Nat Neurosci, 15(10):1407-13, 2012.  PMID: 22922784

  56. Sparvero LJ, Amoscato A, Dixon CE, Long JB, Kochanek PM, Pitt BR, Bayir H, Kagan VE.  Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations. Chem Phys Lipids: 165(5):545-62, 2012.  PMID: 22692104

  57. Kotchey GP, Hasan SA, Kapralov AA, Ha SH, Kim K, Shvedova AA, Kagan VE, Star A.  A Natural vanishing act: the enzyme-catalyzed degradation of carbon nanomaterials.  Acc Chem Res, 45(10):1770-81, 2012. PMID: 22824066

  58. Tkach AV, Yanamala N, Stanley S, Shurin MR, Shurin GV, Kisin ER, Murray AR, Pareso S, Khaliullin T, Kotchey GP, Castranova V, Mathur S, Fadeel B, Star A, Kagan VE, Shvedova AA.  Graphene Oxide, But Not Fullerenes, Targets Immunoproteasomes and Suppresses Antigen Presentation by Dendritic Cells. Small, 288(1):111-21, 2012.  PMID: 22887961

  59. Murray AR, Kisin E, Inman A, Young SH, Muhammed M, Burks T, Uheida A, Tkach A, Waltz M, Castranova V, Fadeel B, Kagan VE, Riviere JE, Monteiro-Riviere N, Shvedova AA.  Oxidative Stress and Dermal Toxicity of Iron Oxide Nanoparticles in Vitro. Cell Biochem Biophys, 2012 Jun 5 [Epub ahead of print].  PMID: 22669739

  60. Kotchey GP, Gaugler JA, Kapralov AA, Kagan VE, Star A. Effect of antioxidants on enzyme-catalyzed biodegradation of carbon nanotubes. Journal of materials chemistry. B, Materials for biology and medicine. 2013; 1 (3):302-309. PMCID: PMC3634595. PMID: 23626907

  61. Schlattner U, Tokarska-Schlattner M, Ramirez S, Tyurina YY, Amoscato AA, Mohammadyani D, Huang Z, Jiang J, Yanamala N, Seffouh A, Boissan M, Epand RF, Epand RM, Klein-Seetharaman J, Lacombe ML, Kagan VE. Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch. The Journal of biological chemistry. 2013 Jan 4; 288 (1):111-21. PMCID: PMC3537004. PMID: 23150663.

  62. Andón FT, Kapralov AA, Yanamala N, Feng W, Baygan A, Chambers BJ, Hultenby K, Ye F, Toprak MS, Brandner BD, Fornara A, Klein-Seetharaman J, Kotchey GP, Star A, Shvedova AA, Fadeel B, Kagan VE. Biodegradation of Single-Walled Carbon Nanotubes by Eosinophil Peroxidase. Small (Weinheim van der Bergstrasse, Germany). 2013 Feb 27. PMID: 23447468

  63. Blasiole B, Bayir H, Vagni VA, Janesko-Feldman K, Cheikhi A, Wisniewski SR, Long JB, Atkins J, Kagan V, Kochanek PM. Effect of Hyperoxia on resuscitation of experimental combined traumatic brain injury and hemorrhagic shock in mice. Anesthesiology. 2013 Mar; 118 (3):649-63. PMID: 23299361

  64. Tyurina YY, Winnica DE, Kapralova VI, Kapralov AA, Tyurin VA, Kagan VE. LC/MS characterization of rotenone induced cardiolipin oxidation in human lymphocytes: Implications for mitochondrial dysfunction associated with Parkinson’s disease. Molecular nutrition & food research. 2013 May 3. PMID: 23650208

  65. Shvedova AA, Tkach AV, Kisin ER, Khaliullin T, Stanley S, Gutkin DW, Star A, Chen Y, Shurin GV, Kagan VE, Shurin MR. Carbon Nanotubes Enhance Metastatic Growth of Lung Carcinoma via Up-Regulation of Myeloid-Derived Suppressor Cells. Small (Weinheim van der Bergstrasse, Germany). 2013 May 27; 9:1691-5. PMCID: PMC3624038. PMID: 22996965

  66. Tkach AV, Yanamala N, Stanley S, Shurin MR, Shurin GV, Kisin ER, Murray AR, Pareso S, Khaliullin T, Kotchey GP, Castranova V, Mathur S, Fadeel B, Star A, Kagan VE, Shvedova AA. Graphene oxide, but not fullerenes, targets Immunoproteasomes and suppresses antigen presentation by dendritic cells. Small (Weinheim van der Bergstrasse, Germany). 2013 May 27; 9:1686-90. PMID: 22887961

  67. Di YP, Tkach AV, Yanamala N, Stanley S, Gao S, Shurin MR, Kisin ER, Kagan VE, Shvedova A. Dual Acute Pro-Inflammatory and Anti-Fibrotic Pulmonary Effects of SPLUNC1 After Exposure to Carbon Nanotubes. American journal of respiratory cell and molecular biology. 2013 May 30. PMID: 23721177

  68. Kochanek PM, Dixon CE, Shellington DK, Shin SS, Bayir H, Jackson EK, Kagan VE, Yan HQ, Swauger PV, Parks SA, Ritzel DV, Bauman R, Clark RS, Garman RH, Bandak F, Ling G, Jenkins LW. Screening of Biochemical and Molecular Mechanisms of Secondary Injury and Repair in the Brain after Experimental Blast-Induced Traumatic Brain Injury in Rats. Journal of neurotrauma. 2013 Jun 5. PMID: 23496248

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