The Malignant Hyperthermia Clinical Grading Scale (CGS) was developed to create a clinical definition for MH syndrome that could serve as a “gold standard” among clinicians and researchers. The scale helps overcome diagnostic difficulties associated with a syndrome, like MH, that has many non-specific and variably present abnormal clinical signs and laboratory findings (listed under the title indicator). The grading scale determines the likelihood that an adverse anesthetic event represents MH based on points that are assigned for abnormal signs and laboratory findings observed during an acute anesthetic reaction (16).