Comparison of Chromosome 7
Draft versus Finished Sequence

Figure 1 Comparison of previous draft sequence with current near-complete sequence of chromosome 7 (ref. 24). At large scale, there was good collinearity between draft and near-complete sequence, although some inversions were present in the draft due to lack of sufficient anchors in some regions. At finer scale, the draft sequence contained some sequence contigs for which order and orientation were not known. The inset shows a region of 500 kb with sequence derived from three overlapping BACs. BACs at each end were finished at the time of draft assembly, whereas the middle BAC was at an early stage of shotgun coverage in which contigs were not yet ordered and oriented.