Slide A demonstrates an increased basement membrane thickness in the child with asthma, (this increase in thickness of the membrane is believed to be part of the airway remodeling or scarring process)

*These pictures are from the same study discussed in the previous few slides. Barbato and colleagues were able to demonstrate that airway remodeling was occurring in children with asthma. Therefore the remodeling was occurring early in the disease process. The authors hypothesize airway scarring to occur parallel with the start of chronic inflammation (rather than the historical belief that remodeling occurs after years of chronic inflammation).