prev next front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |review

These pictures are of airway lumens of the mice. Picture A is from a sedentary mouse and B is from an exercised mouse, both mice had been experimentally induced with an asthmatic state. Notice the difference in airway diameter between the exercised and sedentary mice. The graph represents the differences in inflammatory parameters including: 1) perivascular and peribronchial lymphoid accumulations (*remember that the lymphoid tissues contain lymphocytes- they were measuring leukocyte infiltration). 2) hypertrophy (increase in size)& hyperplasia (which is an increase in number of cells) of the mucosal epithelium; 3) goblet cell and mucin production and(Goblet cells are glandular simple columnar epithelial cells whose sole function is to secrete mucus Mucins which are a family of large, heavily glycosylated proteins which are increased in asthmatics) 4) overall index of inflammation. Notice that the dark lines represent the exercised group which scored lower in all inflammatory parameters! This was my favorite study! Now if we could just reproduce this with some asthmatic school aged children- kiddingJ