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This paradigm looks beyond treatment, representing a shift away from a medical deficit-dysfunction model and from a study of late effects in isolation toward a multidisciplinary focus. It seeks to elucidate the underlying mechanism, biology and biobehavioral basis of sequelae and pays attention to competing causes of morbidity and mortality. As such, it reflects the incredible successes in cancer treatment and early detection
that have enabled the continued growth in numbers of cancer survivors and their expectation to lead rich and fruitful lives.