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The WHO uses the 75 gr.oral glucose load, and the diagnosis is based on the fasting and 2-hr blood glucose levels. In contrast, the NDDG and the Coustan modification, uses a 100 gr. glucose load and the diagnosis is based on four measurements (fasting, 1, 2 and 3 hr. glucose levels). It is also important to note, that the diagnostic blood glucose levels are lower by the NDDG than by the WHO method, and even lower by Coustan’s method. Differences in the diagnostic methods and criteria used in different geographic areas could account, at least in part, for reported differences in the prevalence of GDM.