International Symposium
on
Ligaments & Tendons - ISL&T-XVI

March 18, 2017

Aqua Salon ABC
Hilton San Diego Bayfront
1 Park Boulevard
San Diego, CA 92101



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Preliminary Program
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Preliminary Program

 

Download the schedule in PDF Format here

Podium Sessions

Time Topics Presenting Author
7:30 Registration and Light Breakfast  
8:00 Welcome Zong-Ming Li, PhD
Hongw-Wei Ouyang, MD, PhD
8:10 Clinical Lecture: Biological Strategy in ACL Surgery Chi-Hwa Chen, MD, MBA
 

Podium Session I: Structure and Function of Soft Tissues

Moderators:

8:25 Turkey Model for Flexor Tendon Related Research: An Anatomic and Biomechanical Comparison of Human, Canine, Turkey, and Chicken Flexor Tendons Assaf Kadar, MD
8:35 Discussion  

8:40

Regional Capsular Changes in Length of the Glenohumeral Capsule Underlying the Supraspinatus and Infraspinatus Hansel E. Ihn, BA
8:45 Observation of Chiral Behavior in Tendon Fascicles Kimberly Buchanan, BS
8:50 TCL Thickness Measurement Using Dynamic Ultrasound Imaging Rakshit Shah, BS
8:55 Microstructural Analysis of a Dual-Injury Patellar Tendinosis Mouse Model Dean Wang, MD
9:00 Discussion  
9:10 A Novel Mechanism for Intramuscular Fat Deposition After Muscle Injury Yong-Soo Lee, PhD
9:15 Robust Modeling of Nonlinear History-Dependence of Passive Muscle-Tendon over the Preconditioned Time-Continuum, Gi1en Structure and Key Protein Content Jack Winters, PhD
9:20 Discussion  
9:25 Coffee Break/ Poster Session I (even numbers)  
  Podium Session II: Biomechanics of Tendons and Ligaments Moderators:
9:50 Mechanical Loading Protects Murine Tendon Explants from the Acquisition of Tendinopathic Features

Stefania Wunderli

9:55 Influence of Quasi-Static and Dynamic Cyclic Mechanical Loading on Collagen I Deposition and Tensile/Failure Properties of Engineered Tendon Fibers

Kuwabo Mubyana, BS

10:00 Is Bone Marrow Concentrate Harvested During Arthroscopy from the Humeral Head as Good as Concentrate Harvested from the Iliac Crest? Michael Schär, MD
10:05 Formation of Tendon Organoid by a Defined Uni-Axial Mechanical Loading in 3D Bioreactor Culture

Tao Wang, PhD

10:10 The Effect of Insertion Angle and Pulling Angle on the Pullout Strength of All-Suture Type Anchors - A Biomechanical Study

Hyeon Jang Jeong, MD

10:15 Discussion  
  Podium Session III: ACL Biomechanics, Repair and Regeneration Moderators:
10:30 Decreased Matrix Metalloproteinase 2, 3, 9, and 13 Activity with External Fixation in a Murine Model of Anterior Cruciate Ligament Reconstruction

Yusuke Nakagawa

10:40 Discussion  
10:45 Preclinical Evaluation of the Silk-Based Sheath for Enhanced Osteointegration of Tendon Graft Post Anterior Cruciate Ligament Reconstruction James Goh, PhD
10:50 Knee Joint Center of Rotation in Patients Following Anterior Cruciate Ligament Reconstruction: A Comparison between Hamstring and Patellar Tendon Grafts

Nigel Zheng, PhD

10:55 One Step Method to Promote the Regeneration of ACL Using Composite Silk Scaffold with Autologous Ligament Derived Stem/Progenitor Cell Weiliang Shen, MD
11:00 Varus-Valgus Instability in the Anterior Cruciate Ligament-Deficient Knee: Effect of Posterior Tibial Load

Tomoki Ohori, MD

11:05 Discussion  
11:15 Flash Presentation by Poster Presenters Moderators:
  Podium Session IV: Surgery and Therapeutics Moderators:
11:45 Effect of Low-Intensity Pulsed Ultrasounds after Autologous Adipose-Derived Mesenchymal Stem Cells Transplantation for Tendon-Bone Healing in a Rabbit Model Can Chen, BS
11:55 Discussion  
12:00 Effects of Extracorporeal Shock Wave Therapyon Treating Refractory Patella Tendinitis With Respect To MRI Findings

Yusuke Nishida, MD

12:05 A Novel Technique for Repair of Posterior Medial Menuscus Root Tear: A Biomedical Study Using Porcine Knees

Yu-Shu Lai, PhD

12:10 Immediate Effects of Photobiomodulation Therapy on Achilles Tendon Viscoelastic Properties

Patrick Corrigan, PT, DPT

12:15 Effects of Anteromedial Portal vs. Transtibial ACL Tunnel Preparation on Tibial Tunnel Aperture Contact Characteristics

Charles Lin, BSE

12:20 Discussion  
12:35 Lunch (Group Photo and Poster Viewing)  
  Podium Session V: Tissue Engineering, Regeneration and Healing Moderator:
13:35 Differentiated Tenocytes Revert to a Progenitor-Like State in Mice with Targeted Disruption of TGF-beta Type II Receptor

Guak-Kim Tan, PhD

13:45 Discussion  
13:50 An Unexpected Role for Scleraxis in Skeletal Muscle Regeneration Tyler Harvey, BS
13:55 Alteration of MMPs and TIMPs in a Longitudinal Analysis of Achilles Tendon Tears

Susann Minkwitz, PhD

14:00 Corrosion Characterization of Magnesium Coated via Micro-Arc Oxidation

Jonquil R. Mau, MS

14:05 Effect of Tripeptide Copper Complex GHK-CU on Cultured Healing Cells Derived from Tendon Graft in Anterior Cruciate Ligament Reconstruction

Yuk-Wa Lee, MPhil

14:10 Discussion  
14:20 The Effect of Mesenchymal Stromal Cell Sheets on the Proliferative Stage of Flexor Tendon Healing

Hua Shen, PhD

14:30 Discussion  
14:35 Identity and Tenogenesis of TSPC

Hong-Wei Ouyang, MD, PhD

14:40 Mkx Deficiency Leads to Heterotopic Ossification of Tendon Through Regulation of Angiogenesis

Junxin Lin

14:45 Development of Novel Collagen Scaffold Sheet and Rope for Guided Tendon Regeneration

Minghao Zheng, PhD

14:50 In Vivo Regenerative Potential of various Soft Polymeric Scaffolds in Osteochondral TMJ Defects Alejandro Almarza, PhD
14:55 Discussion  
15:05 Coffee Break/Poster Session II (odd numbers)  
  Podium Session VI: Tendinopathy and Tendinosis Moderators:
15:30 Scleraxis is Essential for Tenocyte Recruitment to Enable Tendon Growth

Deepanwita Pal, PhD

15:35 Rapamycin Decreases Tendon Stem Cell Senescence - A Potential Approach to Treat Aging Induced Tendinopathy

Daibang Nie, PhD

15:40 Statin Treatment is Associated with Trigger Finger and Tendinosis

Per Aspenberg, PhD

15:45 Cited2-Reprogrammed Stem Cells Mitigate Tendinopathy Pathogenesis

Daniel J. Leong, PhD

15:50 Discussion  
  Podium Session VII: Tendon and Ligament Stem Cells Moderators:
.
16:00 Cryopreservation and Reactivation of Human Tendon Derived Stem Cells (hTDSC) Sheet

Sai-Chuen Fu, PhD

16:10 Discussion  
16:15 Human Plantar Fascia Contains Two Populations of Stem Cells Exhibiting Differential Properties

Jianying Zhang, PhD

16:20 Diabetes Mellitus and Calcific Tendinopathy: Hyperglycemia Induces Osteogenic Differention of Tendon Derived Mesenchymal Stem Cells

Alessio Giai Via, MD

16:25 Combination Application of TNF-α and TGF-B1 Facilitate Tenogenic/Osteogenic Differentiation of Tendon-Derived Stem Cells in Vitro

Zhaozhu Li, PhD

16:30 Famotidine, a Histamine-2-Receptor Antagonist, Suppressed Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Patients with Ossification of the Posterior Longitudinal Ligament

Xizhe Liu, MD

16:35 Tenogenic Differentiation of Human Tendon Derived Stem Cells Was Suppressed by MIR124 Through Targeting EGR1

Gang Li, MD, PhD

16:40 Discussion  
  Podium Session VIII: Rotator Cuff Repair and Healing Moderators: Scott Rodeo, MD
.
16:55 A Pilot Study Examining the Feasibility and Safety of Using bone Marrow Aspirate Concentrate I Improving Rotator cuff tendon Healing Following Arthroscopic Rotator Cuff Repair

Camila B Carballo, MSc

17:05 Discussion  
17:10 PARP-1 Inhibition Improves Healing in a Rat Model of Acute Rotator Cuff Repair

Michael B Kuenzler, MD

17:15 Effect of the Allogenic Dermal Fibroblast to Enhance Rotator Cuff Healing in a Rabbit Model of Chronic Rotator Cuff Tear

Sung Min Rhee, MS

17:20 Discussion

 

17:25 Closing Remarks for ISL&T - XVI  
17:35 Proceed to Dinner Venue (Transportation Provided)  
18:30 Banquet and Award Ceremony
 

Poster Sessions

Poster Number Title Presenting Author
1 Comparison of Enlargement and Migration of the Femoral Tunnel Aperture after Anatomic Anterior Cruciate Ligament (ACL) Reconstruction Between Bone-Patella Tendon-Bone (BTB) Grafts and Hamstring Tendon (HT) Grafts

Hiroshi Amano

2 Bioengineered 3D Scaffold for the Controlled Delivery of Cyclic Strain and hGDF-5 to Address hBMSC into Tenogenic Lineage

Nicola Maffulli, MD, PhD

3 Characterization of Tendon Tissue Used as Autograft in Reconstructive Knee Injuries: What Causes the High Failure Rate in Younger Patients?

David Musson, PhD

4 Systematic Reconstructing Lineage Hierarchies of Mous Limb Connective Tissue De1elopment by Using Single Cell RNA-SEQ

Zi Yin, PhD

5 The Effects of an Adipose-Derived Stem Cell Treatment on Chondrometaplasia of Rats' Rotator Cuff Tendons

Saho Tsuchiya

6 Does Sustain Release of Growth Factor Enhance the Healing of Repaired Rotator Cuff Tendon?

Jong Pil Yoon, MD

7 Comparison of the Femoral Tunnel Enlargement After Knee Ligament Reconstruction Surgery Using Hamstring Autograft-Intra-(ACL) vs Extra - (MPFL) Articular Reconstructions

Keisuke Kita, MD, PhD

8 Biomimetic Tendon Extracellular Matrix Composite Gradients for the Ligament-to-Bone Junction Reconstruction

Long Yang, BS

9 A Novel Three-Phased Multilayered Decellularized "Book" Scaffold Provide an Inducti1e Microenvironment for the Proliferation and Differentiation of Bone Marrow Mesenchymal Stem Cells

Xiaoning Li, MD

10 Bridging Suture Makes Consistent and Secure Fixation in Double-Row Rotator Cuff Repair

Teruhisa Mihata, MD, PhD

11 The Expression of NOD1 and IL-1Β In Achilles Tendon Rupture Samples: A Pilot Study

Yuk-Wa Lee, MPhil

12 Assessment of the Anterolateral Aspect of the Sus Scrofa Knee

Gary Ulrich

13 Single Cell RNA Sequencing Analyses Cell Sub-Population of Muscle-Tendon-Junction

Xiao Chen, PhD

14 Mobile Plantar Pressure Loading Assessment in Patients with Achilles Tendon Rupture

Sanna Aufwerber, MSc

15 Assessment of a Novel Method using Ultrasound for Measuring Cross-Sectional Area Along the Length of O1ine Biceps and Infraspinatus Tendons

Sidney J. Perkins

16 Xenografts as an Alternative to Autografts for ACL Reconstruction: 12 Year Results

Kevin R.  Stone, MD

17 mTOR Regulates Differentiation of Tendon Stem/Progenitor Cels (TSCs) - Implication in Pre1enting the Development of Tendinopathy

Jianying Zhang, PhD

18 Effect of LIPUS on the Temporal and Spatial Expression of Tissue Regeneration Related Factors After Rabbit Bone-Tendon Junction Injury

Hongbin Lu, MD, PhD

19 Development and Validation of a 3-D Finite Element Model of a Goat Stifle Joint

Huizhi Wang, BS