School of Engineering
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University of Pittsburgh School of Engineering |
Overview
We propose a project involving a screening device for a condition known as malignant hyperthermia (MH). Malignant hyperthermia (MH) is a rare, acute, genetic condition that is triggered when the patient is exposed to volatile gaseous inhalation anesthetics (the most commonly used agents). Currently, the only way for anesthesiologists to predict MH susceptibility is to perform a muscle biopsy and test the extracted tissue in vitro. This procedure is highly invasive and expensive. We have prototyped a device that would facilitate quick and non-invasive screening of all patients before surgery (in the OR prep or waiting room), and in effect, prevent the onset of MH in susceptible individuals.Images
Deliverable
SBIR Grant Proposal
Design History Files
Specification
Product Design Specification Function Means Object Tree Human Factors Analysis
HFA Failure Mode Effects Analysis
Hazard Analysis w/Fault Tree 510(k)
510(k)
Presentations
BE1160 - Final Presentation - Project Proposal (Dec.5, 2003) BE1161 - Project Update (Feb. 17, 2004) BE1161 - Final Presentation (Apr. 13, 2004)
Team Information
Team Members
Philip Magcalas Sara Doll Lisa Kaczmarski Mentors
Bob Sclabassi, MD, PhD
