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First, we can’t define race/ethnicity very well. Second, given crude classification, there are problems with biased exposure and outcome assessment. For example, biased classification of black participants such as problems in rating, use of diagnostic criteria, and assessment of cultural differences. The authors argue that due to the ethnic homogeneity of the raters (100% white), raters may perceive black participants as sicker than white participants, and thus group them in the more severe categories; The overwhelming exhibition of severe first rank symptoms among blacks may influence raters to follow the diagnostic stem towards schizophrenia; in addition, since diagnoses of severe depression, schizoaffective disorder, and schizophrenia lack clear phenomenological definitions, raters in the study and practitioners in general may have problems differentiating boundaries of each disorder even when using the operationalized instruments of the DSM; these instruments may influence practitioners by allowing them to include secondary symptoms such as hallucinations, etc. as part of the primary diagnosis;

Also, cultural diversity among blacks and whites may affect diagnosis based on fundamental differences; Limitations of the study include a lack of generalizability of results due to a focus on only two ethnic groups, and exclusion of substance abusers which may have led to sampling bias…that is a significantly lower number of blacks; Since the sample was hospital-based, most participants were hospitalized, and therefore, sampling bias may have occurred among the black population.