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Examples of polymorphism are the red blood cell groups in which the different phenotypes of a system by occur in high frequencies in many populations. This, according to Ford’s view, would be unlikely to occur as a consequence of recurrent mutation operating alone to replace a phenotype lost by selection.

Independent of the biological causes for the generation and maintenance of polymorphisms, the concept unifies a large number of interesting biological data. No two people are alike, and polymorphisms probably account for a great deal of variation in humans.