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Vasorelaxation induced by sodium nitrate at pH 2.0 (NO; 1 to 300 ÁM) in aortic rings of normoglycemic rats and 4-week alloxan-diabetic rats treated orally with saline (1 mL/kg) or D-chiro-inositol (20 mg/kg/12h). The data are expressed as mean ▒ SEM of six experiments. * p<0.05, (diabetic + D-chiro-inositol vs. diabetic + saline), ANOVA followed by Bonferroni.