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Primordial prevention deals with underlying conditions leading to exposure to causative factors. The target of this approach is either the total population or selected groups from the population. It aims to modify the conditions that generate and structure the unequal distribution of health damaging exposures, susceptibilities and health protective resources among the population.

The purpose of primary prevention is to limit the incidence of disease by controlling causes and risk factors. It involves two strategies that are often complementary and reflect two views of etiology. It can focus on the whole population with the aim of reducing average risk (the population strategy) or on people at high risk as a result of specific exposure (the high-risk individual strategy).