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Long-term facilitation is synapse-specific and can be captured at another branch by the stimulus that initiates the short-term process.

A. Five puffs of serotonin are applied at the site of initiation (cell A) and produce a synapse-specific facilitation that is shown in part B. This synapse-specific facilitation is not evident at the synapse of cell B unless that synapse is itself primed with a single puff of serotonin. Under those circumstances the long0-term facilitation at synapse A can be captured at synapse B in a reduced from, as illustrated in part C.