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Intervention

Recurrence of breast cancer

Total

+ -
Radical mastectomy (RM) a b a+b
Mastectomy with more limited resection (MLR) c d c+d
Total a+c b+d a+b+c+d
Incidence Rate of recurrence of Breast Cancer for RM = [a/(a+b)] = e%
Incidence Rate of recurrence of Breast Cancer for MLR = [c/(c+d)] = f%

If no significantly different between e% and f%, we can use mastectomy with more limited resection.