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Selected peer-reviewed P.I.'s publications or manuscripts in press.
50. Bellayr I, Vos C, Pan HY, Alston S, Zheng B, Huard J, Li Y. Muscle derived stem cells differentiate into liver-like cells.
49. Mu XD, Peng HR, Pan HY, Huard J, Li Y. Identify differentiated myoblasts by using Cre-Lox technique for skeletal muscle dedifferentiation study.
48. Mu XD, Murrary K, Fu F, Li Y. Relaxin regulates MMP expression in myogenic cells and promotes satellite cell activation during muscle dealing of both young and aged mice. American J Pathology (under review)
47. Bellayr I, Li Y. Stem Cells: It's Good to Have Choices? Journal of the American College of Certified Wound Specialists 2009;1(3):92.
46. Zhu JH, Li Y, Lu AP, Gharaibeh B, Ma JQ, Quintero A, Huard J. Follistatin improves skeletal muscle healing by blocking TGF-beta1-like signaling pathway. JBC (under review)
45. Mu XD, Li Y. Conditional TGF-beta increases stem cell population in C2C12 myoblasts. Experimental Cell Res (in press)
44. Chen XP, Li Y. Role of Matrix Metalloproteinases in Skeletal Muscle: Migration, Differentiation, Regeneration and Fibrosis. Cell Adhesion & Migration 2009;3(4),
43. Mu XD, Wang W, Li Y. Myoblast transplantation and fibrosis prevention in injured and diseased muscle. US Musculoskeletal Review, Volume 4 (1), 2009.
42. Deasy BM, Feduska JM, Payne TR, Li Y, Huard J. Role of Vascular Endothelial Growth Factor (VEGF) on the Vascularization and Fibrosis of Regenerating Skeletal Muscle Tissue/ Fibers. Molecular Therapy 2009;Jul 14. [Epub ahead of print].
41. Bellayr I, Mu XD, Li Y. Biochemical insights into the role of matrix metalloproteinases in the regeneration: challenges and recent developments. Future Medicinal Chemistry 2009;1(6):1095-1111..
40. Wang W, Pan HY, Murray K, Jefferson M, Li Y. MMP1 promotes muscle cells migration and differentiation. American J Pathology 2009 Feb 174(2):541-549. Epub 2009 Jan 15.
39. Kaar J, Li Y, Koepsel R, Blair H, Huard J, Russell A. Matrix Metalloproteinase-1 Treatment of Muscle Fibrosis. Acta Biomater. 2008 Sep;4(5):1411-20. Epub 2008 Apr 7.
38. He F, Zhang Q, Kuruba R, Gao X, Li Y, Gong W, Jiang Y, Xie W, Li S. Upregulation of Decorin by FXR in Vascular Smooth muscle Cells. Biochem Biophys Res Commun. 2008 Aug 8;372(4):746-51. Epub 2008 Jun 2.
37. NozakiM, Li Y, Zhu JH, Ambrosio F, Huard J. Improved muscle healing after contusion injury by the inhibitory effect of suramin on myostatin, a negative regulator of muscle growth. Am J Sports Med 2008 Dec;36(12):2354-62. Epub 2008 Aug 25
36. Bedair HS, Karthikeyan T, Quintero A, Li Y, Huard J. Angiotensin II Receptor Blockade Administered After Injury Improves Muscle Regeneration and Decreases Fibrosis in Normal Skeletal Muscle.Am J Sports Med 2008 Aug;36(8):1548-54. Epub 2008 Jun 11.
35. Shen W, Li Y, Zhu J, Huard J. Interaction Between Macrophages, TGF-beta1, and the COX-2 Pathway During the Inflammatory Phase of Skeletal Muscle Healing After Injury. Journal of Cellular Physiology 2008;214(2):405-412.
34. Zhu JH*, Li Y*, Shen W, Qiao CP, Ambrosio F, Lavasani M, Nozaki M, Branca MF, Huard J. Relationships between TGF- 1, Myostatin, and decorin: Implications for skeletal muscle fibrosis. J Bio Chem 2007 Aug 31;282(35):25852-25863. *First two authors equally contributed to this paper.
33. Bedair H, Liu TT, Kaar J, Shown B, Russell A, Huard J, Li Y. Matrix Metalloproteinase (MMP) Therapy Improves Muscle Healing. Journal of Applied Physiology 2007;102(6):2338-2345.
32. Matsuura T, Li Y, Giacobino JP, Fu FH, Huard J. Skeletal muscle fiber type conversion during the repair of mouse soleus: Potential implications for muscle healing after injury. Journal of Orthopaedic Research. 2007;25(11):1534-1540.
31. Li Y, Li J, Foster W, Tang Y, Xiao X, Huard J. Decorin promotes muscle cell differentiation and muscle regeneration. Molecular Therapy 2007;15(9):1616-1622.
30. Shen W, Prisk V, Li Y, Foster W, Cummins J, Fu F, Huard J. Inhibited skeletal muscle healing in cyclooxygenase-2 gene deficiency mice, the roles of PGE2 and PGF2a in myofiber fusion. J App Physiol 2006;101(4):1215-1221.
29. Shen W, Li Y, Huard J. Musculoskeletal gene therapy, and its potential use in the treatment of complicated musculoskeletal infection. Infectious Disease Clinics of North America 2005;19(4):1007-1022 (review).
28. Shen W, Li Y, Tang Y, Cummins J, Huard J. NS398, a cylooxygenase-2 specific inhibitor, delayed skeletal muscle healing by decreaseing regneration and promoting fibrosis. American J Pathology 2005;167:(4):1105-1117.
27. Negishi S, Li Y, Usas A, Ryosuke K, Foster W, Fu FH, Huard J. The effect of relaxin treatment in skeletal muscle injuries. Am J Spots Medicine 2005;33(12):1816-1824.
26. Chen X, Mao Z, Liu S, Liu H, Wang X, Wu H, Wu Y, Zhao T, Fan W, Li Y, Yew DT, Kindler PM, Li L, He Q, Qian L, Wang X, Fan M. Dedifferentiation of Adult Human Myoblasts Induced by CNTF In Vitro. Molecular Biology of Cell. 2005;16(7):3140-3151.
25. Li Y, Fu, F, Huard J. The use of antifibrosis agents as a novel way to improve muscle healing after sport related muscle injuries. J Physician and Sportsmedicine 2005, 33(5):44-50 (review).
24. Li Y, Negishi S, Sakamoto M, Arvydas Usas, Huard, J. The use of relaxin improves healing in injured muscle. Annals of N. Y. Academic Science. 2005; 1041:395-398.
23. Chan YS, Li Y, Horaguchi T, Foster W, Somogi G, Fu FH, Huard J. The use of suramin, an antifibrotic agent, to improve muscle recovery after strain injury. Am J Sport Medicine 2005; 33(1): 43-51.
22. Li Y, Foster W, Deasy BM, Chan YS, Prisk V, Tang Y, Cummins J, Huard J. TGF-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis. American J Pathology 2004;164(3):1007-1019.
21. Deasy BM, Li Y, Huard J. Tissue Engineering with muscle stem cells. Current Opinion in Biotechnology 2004;15419-15423 (review).
20. Sato K, Li Y, Foster W, Fukushima K, Badlani N, Nodachi N, Usas A, Fu FH, Huard J. Improvement of muscle healing through enhancement of muscle regeneration and prevention of fibrosis. Muscle & Nerve 2003; 28(3):365-372.
19. Foster W, Li Y, Arvydas Usas, George Somogyi, Huard J. gamma-INF as an antifibrotic agent in skeletal muscle. J Orthopeadic Research 2003;21:798-804.
18. Chan YS, Li Y, Horaguchi T, Foster W, Somogi G, Fu FH, Huard J. The antifibrotic effects of suramin in injured skeletal muscle after laceration. J Apply Physiology 2003; 95:771-780.
17. Huard J, Li Y, Peng H, Fu F. Gene therapy & Tissue Engineering for Sport Medicine. J Gene Medicine 2003;5:93-108 (review).
16. Huard J, Yokoyama T, Pruchnic R, Qu Z, Li Y, Lee JY, Somogyi G, de Groat WC, Chancellor MB. The use of muscle derived stem cells for urological dysfunction. Gene Therapy 2002; 9(23): 1617-1626.
15. Li Y, Huard J. Muscle derived stem cell transdifferentiate into myofibroblast in injured muscle. American J Pathology. 2002;161(3): 895-907.
14. Huard J, Li Y, and Fu F. Muscle injury and repair: Current trends in research. Journal of Bone and Joint Surgery 2002;84A:822-832 (review).
13. Li Y, Cummins J and Huard J. Muscle injury and repair. Current Opinion in Orthopaedics 2001;12:409-415 (review).
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12. Li Y*, Han BL, Li K, Jiao LR, Habib N, Wang H. TGF- 1 inhibits HLA-DR and 2-M expression in Hela cells induced with r-IFN. Transplantation Proceedings 1999;31: 2143.
Please also see full list of Dr. Li's publicaitons on:
www.pubmed.com
Dr. Li's Book Chapters
1. Johnny Huard, Baohong Cao, Yong Li, Hairong Peng. Chapter 49. Gene Therapy and Tissue Engineering Based on Muscle-Derived Stem Cells: Potential for musculoskeletal Tissue regeneration and repair. Tissue Engineering And Artificial Organs, Joseph D.(Ed) Bronzino. 2006.
2. Fabrisia Ambrosio, Yong Li, Arvydas Usas, Michael L. Boninger, Johnny Huard. Chapter 22. Muscle Repair After Injury and Disease. Musculoskeletal Tissue Regeneration Biological Materials and Methods Series: Orthopedic Biology and Medicine
Pietrzak, William S. (Ed.) Hardcover. 2007
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