Tiffany's Homepage

*My name is Tiffany

*My major is Biology with an emphasis on Pre-dental medicine

*My favorite thing about college is being able to set my own boundaries

*My favorite foods are Lemons and Grapefruits

*My favorite quotation is "Sadness is beautiful, loneliness is tragic…"

*My favorite bands are silverchair, Bush, Disturbed, and anybody I see live in concert

*What I am most proud of are all of my accomplishments up to this point no matter how small or trivial they may seem to others.

*What I would like my life to be like 10 years from today: I'll be two years out of dentistry school. Hopefully I'll be in the process of starting my own practice in Pittsburgh, but no matter what I'll be living a happy, fulfilled life.


A Neuroscience Topic That Interests Me...


Neurobiology and Depression

Depression can be looked at from many directions. Two such ways are from the biological view or the psychological view. The main focus of this paper will be from the biological side.


The symptoms of mental illness creep over you like a cold damp fog. The number of people at probable risk of depression is climbing, up from 5.2 percent in 1994/95 to 7.1 percent in 2000/01 (Hawaleshka, 38). One particular subject, Sarah Hamid started feeling the symptoms of depression at age 18. Sarah got to the point where she was sleeping 12-16 hours a day and crying uncontrollably. "It got to the point where I was driving home one day and I really wanted to drive the car over the yellow line into oncoming traffic." That is when Sarah knew it was time to seek help.


The biological side of depression takes the approach of centering on the study of the brain. The brain is made up of a complex network of nerve cells which are called neurons. It is also made of brain chemicals called neurotransmitters. Just as the name says, the neurotransmitters transmit messages from one neuron to another. Two specific neurotransmitters, norepinephrine and serotonin, are not produced in sufficient quantities in a depressed person's brain. It is thought that because of the lack of chemicals, too few messages get transmitted between neurons and depressive symptoms occur (Nestler, 1).


New technology allows researchers to take pictures of the brain that show activity levels in the brain. These imagining techniques, such as functional Magnetic Resonance Imaging (f-MRI) and Positron Emission Tomography (PET), scan the brain. The scans create images which show the amount of activity in different parts of the brain. Some studies with these kinds of techniques have suggested that the patterns of activation in the brains of depressed people are different than those who are not. These tests can help doctors and researchers lean more about depression and other mental illnesses (Nestler, 2).


Failure to recognize and treat depressive disorder leaves the patient to suffer and to become a costly user of health care services. Depression that is not treated significantly increases the risk of mortality. Depressive disorders can also be linked to patients with Parkinson's disease, Dementia, or Alzheimer's disease. Treatment of the depressive disorder may enable the patient to achieve better functioning in activities, daily living; possibly to a degree that placement in a nursing facility may be delayed or avoided (McCahill, 1).


Sarah Hamid got lucky in her case, because she knew she needed assistance with depression and seeked help for it. Her doctor diagnosed severe depression and Sarah now takes an effective anti-depressant (Hawaleshka, 38). The symptoms of depression may never go away, Sarah still experiences crying fits every few months or so, but I'm sure she's a lot happier and her depression is slowly fading away.


Works Cited

Hawaleshka, Danylo. "Trouble Spots." Maclearis Health Report. 2 October 2002: 38-42

McCahill, Margaret. "Screening for depression." American Family Physician. 15 September 2002: 1-3.

Nestler, E.J. "What is Depression?: Biological Cause." Depression Clinic. http://www1.depressionclinic.com/db/PageReq?SessionID=72759475.