Vladimir Tyurin

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Department of Environmental and Occupational Health

Vladimir Tyurin - Publications - past 5 years

Kagan VE, Bayır HA, Belikova NA, Kapralov O, Tyurina YY, Tyurin VA, Jiang J, Stoyanovsky DA, Wipf P, Kochanek PM, Greenberger JS, Pitt B, Shvedova AA,Borisenko G. Cytochrome c/cardiolipin relations in mitochondria: A kiss of death. Free Radic Biol Med. 2009 Mar 11. PMID: 19285551

Bayir H., Kapralov A.A., Jiang J., Huang Z., Tyurina Y.Y., Tyurin V.A., Zhao Q., Belikova N.A., Vlasova I.I., Maeda A., Zhu J., Na H.M., Mastroberardino P.G., Sparvero L.J., Amoscato A.A., Chu C.T., Greenamyre J.T., Kagan V.E. Peroxidase mechanism of lipid dependent cross-linking of synuclein with cytochrome c: protection against apoptosis versus delayed oxidative stress in Parkinson's disease. J. Biol. Chem., 2009, 284(23): 15951-15969.

Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Mar 13. PMID: 19328050

Belikova NA, Tyurina YY, Borisenko G, Tyurin VA, Samhan Arias AK, Yanamala N, Furtmuller PG, Klein-Seetharaman, Obinger C, Kagan VE. Heterolytic reduction of fatty hydroperoxides by cytochrome c-cardiolipin complexes: antioxidant function in mitochondria. Am Chem Soc. 2009 Aug 19;131(32):11288-9. PMID: 19627079

Tyurina YY, Tyurin VA, Kapralova VI, Amoscato AA, Epperly MW, Greenberger JS, Kagan VE. Mass-spectrometric characterization of phospholipids and their hydroperoxide derivatives in vivo: effects of total body irradiation. Methods Mol Biol. 2009;580:153-83. PMID: 19784599

Tyurin VA, Tyurina YY, Ritov VB, Lysytsya A, Amoscato AA, Kochanek PM, Hamilton R, Dekosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues. Methods Mol Biol. 2010;610:353-74. PubMed PMID: 20013189

Li W., Wu S., Ahmad M., Jiang J., Liu H., Nagayama T., Rose M.E., Tyurin V.A., Tyurina Y.Y., Borisenko G.G., Belikova N., Chen J., Kagan V.E., Graham S.H. The cyclooxygenase site, but not the peroxidase site of cyclooxygenase-2 is required for neurotoxicity in hypoxic and ischemic injury. J. Neurochem., 2010, 113(4), 965-977. PMID: 20236388

Tyurina Y.Y., Tyurin V.A., Kaynar A.M., Kapralova V.I., Wasserloos K.J., Li J., Mosher M., Wright L., Wipf P., Watkins S.K., Pitt B.R., Kagan V.E. Oxidative lipidomics of hyperoxic acute lung injury: Mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Am. J. Physiol. Lung Cell Mol. Physiol. 2010, Apr 23. PMID: 20418384

Herber D.L., Cao W., Nefedova Y., Novitskiy S.V., Nagaraj S., Tyurin V.A., Corzo A., Cho H.I., Celis E., Lennox B., Knight S.C., Padhya T., McCaffrey T.V., McCaffrey J.C., Antonia S., Fishman M., Ferris R.L., Kagan V.E., Gabrilovich D.I. Lipid accumulation and dendritic cell dysfunction in cancer. Nature. Med., 2010, 16(8), 880-6. PMID:20622859

Tyurina YY, Tyurin VA, Kapralova VI, Wasserloos K, Mosher M, Epperly MW, Greenberger JS, Pitt BR, Kagan VE. Oxidative lipidomics of ϒ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Radiat Res. 2011 May;175(5):610-21. Epub 2011 Feb 21. PMID:21338246

Tyurin VA, Cao W, Tyurina YY, Gabrilovich DI, Kagan VE. Mass-spectrometric characterization of peroxidized and hydrolyzed lipids in plasma and dendritic cells of tumor-bearing animals. Biochem Biophys Res Commun. 2011 Sep 16;413(1):149-53. Epub 2011 Aug 22. PubMed PMID: 21872574

Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayîr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE. A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death. Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499. PubMed PMID: 21988913

Tyurina YY, Tungekar MA, Jung MY, Tyurin VA, Greenberger JS, Stoyanovsky DA, Kagan VE. Mitochondria targeting of non-peroxidizable triphenylphosphonium conjugated oleic acid protects mouse embryonic cells against apoptosis: Role of cardiolipin remodeling. FEBS Lett. 2011 Dec 28. PubMed PMID: 22210054

Stoyanovsky DA, Huang Z, Jiang J, Belikova NA, Tyurin V, Epperly MW, Greenberger JS, Bayir H, Kagan VE. A manganese-porphyrin complex decomposes H₂O₂, inhibits apoptosis, and acts as a radiation mitigator in vivo. ACS Med Chem Lett. 2011 Nov 10;2(11):814-817. PubMed PMID: 22247787

Samhan-Arias AK, Ji J, Demidova OM, Sparvero LJ, Feng W, Tyurin V, Tyurina YY, Epperly MW, Shvedova AA, Greenberger JS, Bayir H, Kagan VE, Amoscato AA. Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin. Biochim Biophys Acta. 2012 Mar 23. PMID: 22464971

Ji J, Kline AE, Amoscato AA, Samhan-Arias AK, Sparvero LJ, Tyurin VA, Tyurina YY, Fink B, Manole MD, Puccio AM, Okonkwo DO, Cheng JP, Alexander H, Clark RS, Kochanek PM, Wipf P, Kagan VE, Bayir H. Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury. Nat Neurosci. 2012, 15(10), 1407-13. PMID: 22922784

Tyurin VA, Yanamala N, Tyurina YY, Klein-Seetharaman J, Macphee CH, Kagan VE. Specificity of lipoprotein-associated phospholipase A(2) toward oxidized phosphatidylserines: liquid chromatography-electrospray ionization mass spectrometry characterization of products and computer modeling of interactions.Biochemistry. 2012 Dec 4;51(48):9736-50. doi: 10.1021/bi301024e. Epub 2012 Nov 19. PMID: 23148485

Tyurina YY, Winnica DE, Kapralova VI, Kapralov AA, Tyurin VA, Kagan VE. LC/MS characterization of rotenone induced cardiolipin oxidation in human lymphocytes: Implications for mitochondrial dysfunction associated with Parkinson's disease. Mol Nutr Food Res. 2013 May 3. PMID: 23650208

Chu CT, Ji J, Dagda RK, Jiang JF, Tyurina YY, Kapralov AA, Tyurin VA, Yanamala N, Shrivastava IH, Mohammadyani D, Qiang Wang KZ, Zhu J, Klein-Seetharaman J, Balasubramanian K, Amoscato AA, Borisenko G, Huang Z, Gusdon AM, Cheikhi A, Steer EK, Wang R, Baty C, Watkins S, Bahar I, Bayir H, Kagan VE. Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. Nature Cell Biology. 2013 Oct; 15 (10):1197-205. PMCID: PMC3806088. PMID: 24036476

Fabisiak JP, Tyurina YY, Tyurin VA, Kagan VE. Quantification of selective phosphatidylserine oxidation during apoptosis. Methods in Molecular Biology (Clifton, N.J.). 2014; 1105:603-11. PMID: 24623255

Ramakrishnan R, Tyurin VA, Veglia F, Condamine T, Amoscato A, Mohammadyani D, Johnson JJ, Zhang LM, Klein-Seetharaman J, Celis E, Kagan VE, Gabrilovich DI. Oxidized lipids block antigen cross-presentation by dendritic cells in cancer. Journal of Immunology (Baltimore, Md. : 1950). 2014 Mar 15; 192 (6):2920-31. PMCID: PMC3998104. PMID: 24554775

Tyurina YY, Domingues RM, Tyurin VA, Maciel E, Domingues P, Amoscato AA, Bayir H, Kagan VE. Characterization of cardiolipins and their oxidation products by LC-MS analysis. Chemistry and Physics of Lipids. 2014 Apr; 179:3-10. PMCID: PMC4025908. PMID: 24333544

Fazzi F, Njah J, Di Giuseppe M, Winnica DE, Go K, Sala E, St Croix CM, Watkins SC, Tyurin VA, Phinney DG, Fattman CL, Leikauf GD, Kagan VE, Ortiz LA. TNFR1/phox interaction and TNFR1 mitochondrial translocation Thwart silica-induced pulmonary fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 2014 Apr 15; 192 (8):3837-46. PMCID: PMC3977215. PMID: 24623132

Tyurin VA, Balasubramanian K, Winnica D, Tyurina YY, Vikulina AS, He RR, Kapralov AA, Macphee CH, Kagan VE. Oxidatively modified phosphatidylserines on the surface of apoptotic cells are essential phagocytic ‘eat-me’ signals: cleavage and inhibition of phagocytosis by Lp-PLA2. Cell Death and Differentiation. 2014 May; 21 (5):825-35. PMCID: PMC3978307. PMID: 24464221

Tyurina YY, Poloyac SM, Tyurin VA, Kapralov AA, Jiang J, Anthonymuthu TS, Kapralova VI, Vikulina AS, Jung MY, Epperly MW, Mohammadyani D, Klein-Seetharaman J, Jackson TC, Kochanek PM, Pitt BR, Greenberger JS, Vladimirov YA, Bayir H, Kagan VE. A mitochondrial pathway for biosynthesis of lipid mediators. Nature Chemistry. 2014 Jun; 6 (6):542-52. PMID: 24848241

Shukolyukov SA, Tyurin VA. [Retinal pigments and carotenoids of the light-shading “spectacles” of the greenling Hexagrammus octogrammus]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 1217287

Tiurina IuIu, Sokolova TV, Gonchar VS, Furaev VV, Avrova NF, Tiurin VA. [Inhibition of Na, K-adenosine triphosphatase by glutamate in cerebral cortex synaptosomes. Protective effect of alpha-tocopherol and superoxide dismutase]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 9783381

Tiurin VA, Tiurina IuIu, Sokolova TV, Arduini A. [The participation of palmitic acid in repair of synaptosome membranes during oxidative stress. The role of palmitoylcarnitine in adaptation mechanism]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 9720146

Tiurina IuIu, Tiurin VA, Furaev VV, Rychkova MP, Etingof RN. [The role of saturated and unsaturated fatty acids in the repair of the lipid bilayer of photoreceptor membranes in photodamage: the possible mechanism of adaptation]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 9703665

Tiurin VA, Arduini A, Tiurina IuIu, Sokolova TV, Furaev VV, Rychkova MP, Arrigoni-Martelli E. [The repair of the membrane lipid bilayer in oxidative stress: phosphatidylethanolamine reacylation in synaptosome, photoreceptor and erythrocyte membranes]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 9148613

Avrova NF, Nalivaeva NN, Tiurin VA, Vetosh AN, Tiurina IuIu, Baev VA, Vasil’va IV. [Ability of gangliosides to improve the functional state of the body and normalize the biochemical structure of cell membranes in hypoxia]. Fiziologiia cheloveka. PMID: 8138079

Kreps EM, Tiurin VA, Chelomin VP, Gorbunov NV, Nalivaeva NN. [Mechanisms of the initiation of lipid peroxidation in the synaptosomes of marine teleosts]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 3673367

Kagan VE, Tiurin VA, Gorbunov NV, Prilipko LL, Chelomin VP. [Is a change in the microviscosity and asymmetrical distribution of phospholipids in the membrane a necessary condition for signal transmission? A comparison of the mechanisms of signal transmission in the plasma membranes of the brain synaptosomes. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 6322483

Tiurin VA, Gorbunov NV. [Fatty acid composition of aminophospholipids of the protein microenvironment in synaptosome plasma membranes in the rat brain]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 6659759

Tiurin VA, Berman AL, Rychkova MP, Chelomin VP, Korchagin VP. [Fatty acid composition of the bilayer phospholipids in the photoreceptor membranes and aminophospholipids from the rhodopsin microenvironment of warm-blooded and cold-blooded vertebrates]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 6979137

Novikov KN, Shvedova AA, Tiurin VA, Shukoliukov SA, Kagan VE. [Role of lipid composition in the kinetics of free radical lipid oxidation in photoreceptor membranes]. Biofizika. PMID: 911925

Tiurin VA, Korchagin VP, Shukoliukov SA, Fedosov IuV. [Temperature decolorization of the rhodopsin of bulls and Theragra chalcogramma fish]. Zhurnal evoliutsionnoi biokhimii i fiziologii. PMID: 868374

Books and Book Chapters

Tyurin V.A., Tyurina Y.Y., Ritov V.B., Lysytsya A., Amoscato A.A., Kochanek P.M., Hamilton R., DeKosky S.T., Greenberger J.S., Bayer H., Kagan V.E. Oxidative lipidomics of apoptosis: Quantitative assessment of phospholipid hydroperoxides in cells and tissues. Methods in Molecular Biology, 2010, 610, 353-374.

Tyurina YY, Tyurin VA, Kapralova VI, Amoscato AA, Epperly MW, Greenberger JS, Kagan VE. Mass-Spectrometric Characterization of Phospholipids and Their Hydroperoxide-Derivatives in Vivo: Effects of Total Body Irradiation. Methods in Molecular Biology, 580, Chapter 9, 2009.

Tyurin VA, Tyurina YY, Kochanek PM, Hamilton R, DeKosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of programmed cell death. Methods Enzymol. 442:375-393, 2008.

Invited Articles

Samhan-Arias AK, Ji J, Demidova OM, Sparvero LJ, Feng W, Tyurin V,A. Tyurina YY, Epperly MW, Shvedova AA, Greenberger JS, Bayır H, Kagan VE, Amoscato AA. Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin. Biochim Biophys Acta. 2012 Mar 23. [Epub ahead of print], PMID: 22464971

Tyurin V.A., Tyurina Y.Y., Jung M.Y., Tungekar M.A., Wasserloos K.J., Bayır H., Greenberger J.S., Kochanek P.M., Shvedova A.A., Pitt B., Kagan V.E. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2009, Mar 13.
Kagan V.E., Bayır H.A., Belikova N.A., Kapralov O., Tyurina Y.Y., Tyurin V.A., Jiang J., Stoyanovsky D.A., Wipf P., Kochanek P.M., Greenberger J.S., Pitt B., Shvedova A.A., Borisenko G. Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. Free Radic. Biol. Med., 2009 Mar 12.

Review Articles

Kagan V.E., Bayır H.A., Belikova N.A., Kapralov O., Tyurina Y.Y., Tyurin V.A., Jiang J., Stoyanovsky D.A., Wipf P., Kochanek P.M., Greenberger J.S., Pitt B., Shvedova A.A., Borisenko G. Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. Free Radic. Biol. Med., 2009 Mar 12.

Published Abstracts

Kagan VE, Jiang AND Kagan VE, Huang Z, Tyurin VA, Tyurina Y, Stolz D, Watkins S, Mallampalli R. Signaling Role of Cardiolipin Externalization in Elimination of Damaged Mitochondria in Lung Epithelial Cells [abstract]. In: 53rd Annual Meeting for Society of Toxicology; The Toxicologist. 2014 Mar 23-27 ; Phoenix, Arizona Reston, VA: Society of Toxicology, 2014. 261

Tyurin VA, Cao W, Amoscato AA, Loomen L, Gabrilovich D, Kagan VE. Redox Cross-Talk between Myeloid-Derived Suppressor Cells and Dendritic Cells in Cancer: Accumulation of Oxygenated Lipid Droplets and Suppression of Antigen Cross-Presentation [abstract]. In: 53rd Annual Meeting for Society of Toxicology; The Toxicologist Supplement to Toxicological Sciences. 2014 Mar 23-27 ; Phoenix, Arizona Reston, VA: Society of Toxicology, 2014. 260-261

Tyurin VA, Cao W, Loomen J, Kagan VE, and Gabrilovich D. Lipid Droplets with Oxygenated Fatty Acids and Triglycerides in Dendritic Cells: Possible Role in Antigen Presentation in Cancer. In: 52nd Annual Meeting for Society of Toxicology; The Toxicologist, v.132, Abstract No 2008, 2013 Mar 10-14 ; San Antonio, TX 2013. 428

Star A, Kapralov A, Amoscato AA, Tyurin VA, Seo W, Epperly M, Greenberger JS, Tyurina YY, Kagan VE. Development of a Mitochondria-Targeted Nano-Complex of Imidazole-Substituted Oleic Acid As a Radiomitigator. In: 52nd Annual Meeting for Society of Toxicology; The Toxicologist, v.132, Abstract No 2009, 2013 Mar 10-14; San Antonio, TX 2013. 428

Kagan VE, Tyurin VA, Poloyac SM, Epperly M, Greenberger JS, Bayir H, Tyurina YY. Mitochondrial cardiolipin as a substrate for cytochrome c-catalyzed production of oxygenated lipid mediators [abstract]. In: 52nd Annual Meeting for Society of Toxicology; The Toxicologist, v.132, Abstract No 2010, 2013 Mar 10-14; San Antonio, TX 2013. 428

Tyurina YY, Winnica DE, Kapralova VI, Tyurin VA, Kagan VE. Cardiolipin as a biomarker of mitochondrial dysfunction associated with Parkinson’s disease. [In: 52nd Annual Meeting for Society of Toxicology; The Toxicologist, v.132, Abstract No 1888, 2013 Mar 10-14; San Antonio, TX 2013. 401

Tyurin VA, Zhao H, Tyurina YY, Epperly MW, Greenberger JS, Kagan VE. Monolyso-cardiolipin – biomarker of mitochondrial dysfunction induced by total body irradiation. LC-ESI-MS study. 51th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.126, Suppl. 1, Abstract No. 2034, p.438, March 11-15, 2012, San Francisco CA

Tyurina YY, Tungekar MA, Jung MY, Tyurin VA, Stoyanovsky SA, Kagan VE, Mitochondria targeting of non-peroxidizable triphenylphosphonium conjugated oleic acid protects mouse embryonic cells against apoptosis: Role of cardiolipin remodeling. 51th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.126, Suppl. 1, Abstract No. 2035, p.438, March 11-15, 2012, San Francisco CA

Kagan VE, Tyurin VA, Balasubramanian K, Winnica D, Tyurina YY, Macphee CH, Role of oxygenated phosphatidylserine and its metabolitis – lyso-phosphatidylserines produced after oxidation and hydrolysis by plasma lipoprotein-associated phospholipase A2 in clearance of apoptotic cells by macrophages: LC-ESI-MS study. 51th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.126, Suppl. 1, Abstract No. 2056, p.443, March 11-15, 2012, San Francisco CA

Frostegård J., Tyurin VA, Tyurina YY, Amoscato A, Su J, Balasubramanian KK, Maeda A, Fadeel B, Greenberger JS, Mallampali RK, Kagan VE. Interrelationships of peroxidation and immunogenicity of cardiolipin: an oxidative lipidomics approach. 51th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.126, Suppl. 1, Abstract No. 760, p.165, March 11-15, 2012, San Francisco CA

Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova N, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayîr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE, A mitochondria-targeted imidazole-substituted fatty acids inhibit cytochrome c peroxidase and mitigate radiation induced death. 51th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.126, Suppl. 1, Abstract No. 2036, p.439, March 11-15, 2012, San Francisco CA

Cao W, Tyurin VA, Tyurina YY, Gabrilovich DI, Kagan VE. Oxygenated fatty acids in plasma of tumor-bearing animals stimulate their scavenger receptor A1-mediatd up-take by dendritic cells: Mass-spectrometric evidence. 51th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.126, Suppl. 1, Abstract No. 1624, p.351, March 11-15, 2012, San Francisco CA

Samhan-Arias AK, Tyurin VA, Tyurina YY, Bayır H, Kagan VE, Amoscato AA. 2D-LC-MS analysis of oxidized lipid species: Application to the study of cardiolipin in apoptosis and damaged tissue. 51th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.126, Suppl. 1, Abstract No. 1180, p.254, March 11-15, 2012, San Francisco CA

Tyurin V.A., Tyurina Y.Y., Macphee C.H., Kagan V.E. LC-ESI/MS reveales unusual oxygenated lysophosphatidylserines prodiced after oxidation and hydrolysis by plasma lipoprotein-associated phopsholipase A2 of sn-1, sn-2-dilinoleoyl-PS. 50th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. 2, V.120, Abstract No. 1669, p.359, March 6-10, 2011, Washington DC

Tyurina Y., Tyurin V., Sparvero L., Amoscato A., Kapralova V., Kisin E., Murray A., Shi J., Fadeel B., Shvedova A., Kagan V. Oxidative lipidomics reveals selective, but not random, pulmonary phopsholipid peroxidation after inhalation of carbon nanotubes. 50th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. 2, V.120, Abstract No. 1170, p.252, March 6-10, 2011, Washington DC.
Tyurin V.A., Winnica D., Fazzi F., Feng W., Tyurina Y.Y., Stewart N.A., Kisin E.R., Murray A.R., Shvedova A.A., Pitt B.R., Kagan V.E., Ortiz L.A. Phospholiopid oxidative metabolism during macrophage response to environmental agents. 49^th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.114, No 1, Abstract No. 599, p.128, March 8-11, 2010, Salt Lake City, UT.

Tyurina Y.Y., Tyurin V.A., Kapralova V.I., Wasserloos K., Mosher M., Epperly M., Greenberger J., Pitt B., Kagan V.. Oxidative lipidomics of gamma-radiation induced lung injury. 49^th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.114, No 1, Abstract No. 597, p.128, March 8-11, 2010, Salt Lake City, UT.

Kagan V.E., Tyurin V.A., Kapralova V., Kaynar M., Wasserloos K., Mosher M., Wipf, P., Pitt B., Tyurina Y.Y. Oxidative lipidomics of hyperoxia-induced acute lung injury. 49^th Annual Meeting for Society of Toxicology; The Toxicologist: Suppl. V.114, No 1, Abstract No. 598, p.128, March 8-11, 2010, Salt Lake City, UT.

Tyurin VA, Jung MY, Tyurina YY, Prieto T, Zhao Q, Kapralov AA, Belikova NA, Nantes I, Kagan VE Cardiolipin oxidation, hydrolysis and accumulation of monolysocardiolipins and oxidized free fatty acids during apoptosis: Role cytochrome c. 302#448, 48^th Annual Meeting, Society of Toxicology, Baltimore, MD, March, 2009.

Feng W, Tyurin VA, Go KI, Tyurina YY, Stewart NA, Fazzi F, Kisin ER, Murray AR, Shvedova AA, Pitt BR, Ortiz LA, Kagan VE Oxidative lipidomics of macrophage activation and apoptosis induced by phagocytosis of particles and pathogens., 936#434. 48^th Annual Meeting, Society of Toxicology, Baltimore, MD, March, 2009.

Tyurina YY, Tyurin VA, Kapralova VI, Tugekar A, Kaynar M, Wasserloos K, Mosher M, Epperly M, Greenberger JS, Pitt BR, Kagan VE. Oxidative lipidomics of acute lung injury induced by hyproxia and gamma-irradiation. 949#447. 48^th Annual Meeting, Society of Toxicology, Baltimore, MD, March, 2009.

Tyurin V.A., Zhao Q., Mnuskin A., Hamilton R.L., DeKosky S.T., Reynolds W.F. and Kagan V.E. Phospholipid peroxidation biomarkers of Alzheimer’s disease in the brain: selective oxidation of phosphatidylserine. 47^th Annual Meeting, Sosiety of Toxicology, Seattle, WA, The Toxicologist, # 1961, p. 404, 2008.

Borisenko G.G., Kapralov A., Tyurin V.A., and Kagan V.E. Modified cardiolipin homologues as inhibitors of pro-apoptotic peroxidase function of cytochrome c. 47^th Annual Meeting, Sosiety of Toxicology, Seattle, WA, The Toxicologist, # 1392, p. 285, 2008.