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Department of Environmental and Occupational Health

Vladimir Tyurin - Grants

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Year Title

Position
3/1/1997- 6/30/2011 University of Pittsburgh Brain Trauma Research Center-Core A

Co-investigator
6/14/2002- 1/31/2008 Preeclampsia Mechanisms and Post Pregnancy Implications

Co-investigator
9/30/2003- 5/31/2008 Mechanisims of Cytoprotection in acute lung injury

Co-investigator
6/1/2005- 5/31/2009 Center for Excellence in Detection, Diagnosis and Intervention in Dementia

Co-investigator
2/13/2006- 2/12/2008 Novel Strategies in Experiemental Traumatic Brain Injury

Co-investigator
07/01/08-06/30/10 Lung Oxidative Stress Inflammation by Carbon Nanotubes

Co-investigator
2008 - 2013 Oxidative Lipidomics of Pulmonary Apoptosis in Hyperoxia Co-investigator
07/17/09-06/30/10 Divergent Pathways of Cell Death after Brain Injury

Co-investigator
09/01/09-08/31/10 Irradiation Damage and Protection of Pulmonary Endothelium Oxidative Lipidomics

Co-investigator
08/31/10 Role of Cardiolipin Oxidation after Traumatic Brain Injury in Immature Rat

Co-investigator
9/1/10-5/31/11 Mechanisms and Prevention of Etoposide-Induced Leukemia

Co-investigator
2010 - 2012 Regulation of lyso-phospholipids for radiomitigation. Peroxidized and phospholipase A–modified phospholipids in radiation-induced apoptosis as possible targets for radiomitigation Principal Investigator
2010-2011 Regulation of lyso-phospholipids for radiomitigation. Peroxidized and phospholipase A–modified phospholipids in radiation-induced apoptosis as possible targets for radiomitigation.
Co-investigator
06/01/10-05/31/11 Oxidative Lipidomics of Pulmonary Endothelial Apoptosis in Hyperoxia

Co-investigator
09/15/11 Novel Mitochondrial  Targeted drugs for Treatment of the Irradiation-Induced Hematopoietic Syndrome Co-investigator
2011 - 2013 Phosphatidylserine and its peroxidized and Lp-PLA2-hydrolyzed species on cell surface: Role in clearance of apoptotic cells by macrophages  
2012 - 2013

Complexes of mitochondria-targeted XJB 5-131 bound to branched polyethylene glycol functionalized carbon nanotubes will prolong its half-life in blood circulation and enhance tissue uptake and intracellular distribution, ultimately improving its efficiency as a radiation mitigator.

Principal Investigator
2012 - 2016 Oxygenated Species of Cardiolipins as Biomarkers of Mitochondrial Dysfunction Co-investigator
2012 - 2017 Molecular and Cellular Control of Placental Metabolism - Project 3 Co-investigator
2012 - 2017 Lipids and Myeloid Cell Function in Cancer Co-investigator
2012 - 2017 Mapping Lipid Oxidation in Traumatic Brain Injury by mass s Spectrometric Imaging Co-investigator
2013 - 2017 Oxidative Lipidomics Core (Core B) Co-investigator