Just to give you a little bit of data from some stuff that we’ve done. We looked at the relationship between cardiovascular disease and back pain. This is the SOF population. Here I would highlight just a couple of things. People with cardiovascular disease are two and one half times more likely to have report severe back pain than people without it and are more likely to report days of limited activities because of that back pain. Interestingly, they don’t stay in bed any more because of it. But there are many, many, many factors that come into whether people report back pain or not. This is a study that we did also in SOF and this study on pain by Musgrave, who is one of our residents in orthopedic surgery and we looked at use of estrogen replacement therapy in the elderly.