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The first analysis was a comparison of the basal characteristics of the three groups using the X2 tests for qualitative variables and Snedecor's F test for quantitative variables. To analyse the main outcome, the relative reduction (RR) in the number of prescriptions of each type of NSAID was calculated as the average number of packages of each drug prescribed per doctor and per month during the six months after the intervention, minus the average number of packages pre-scribed per doctor, per month during the six previous months, divided by the latter. Significant differences were established in function of the confidence intervals of 95% (95%CI) of this reduction.