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Bone mass reflects a balance between bone formation and bone loss. The balance is tipped in favor of bone mass accretion during childhood and adolescence. Like overall growth in height and weight, bone mass increases substantially during the first few years of life, then slows down until the onset of puberty when another marked increase occurs, ending at about age 16 to 18 years. The patterns and amount of bone mass for girls and boys are generally similar during childhood; however, puberty-related growth generally occurs at a younger chronological age for girls than for boys. During puberty, bone mass increases faster in boys than in girls and males eventually achieve a higher peak bone mass than females. For both boys and girls the greatest change in bone mass per year occurs one-half year to one year after their greatest change in height per year. During the pubertal growth spurt as much as 60% of peak bone mass is achieved. Of great importance is the recognition that, for both sexes, as much bone is accrued during these adolescent years as most individuals will lose during all of adult life (5).

Exactly when peak bone mass is achieved is still unclear, but most of the process is completed by the late teens for females and early twenties for males, although small increases in lumbar spine and other skeletal regions continue until the late twenties or early thirties. For both men and women, there is then a stable period through early and middle adulthood until about 50 years of age when bone mass losses can be detected. This loss is accelerated in women during the three to six years immediately after menopause. Slower but continual bone mass loss and internal supporting structural losses continue with age for both women and men. Eventually, bones can become so weak that they readily fracture.

5. Kemper HCG. Skeletal development during childhood and adolescence and the effects of physical activity. Pediatric Exerc Sci 2000;12:198-216.

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