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i) reaction with biological molecules which may increase solvation or transport (carriers, etc.) but may also decrease transport.

ii) ciliary movement (nasopharynx, trachea, bronchial tree down to terminal bronchiole) will move particles deposited on the mucus layer.

iii) phagocytosis of particles by macrophages and clearance via ciliary-mucus transport.

iv) transport of insoluble particle across alveolar epithelium into lymphatics