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Coronavirus

Structural Protein	Functional Protein
Nucleocapsid Protein (N)	•Bound to RNA genome to make up nucleocapsid
Spike Protein (S)	•Critical for binding of host cell receptors to facilitate entry of host cell
Envelop Protein (E)	•Interacts with M to form viral envelop
Membrane Protein (M)	•Central organizer of CoV assembly •Determines shape of viral envelop
NOTE: Some CoV’s do not need to have the full ensemble of structural proteins to make virions, highlighting that certain proteins may be dispensable or compensated by the function of non-structural proteins.