 |
But we
can do better than this. The cohort study gives us gold-standard mortality information.
The cohort population confirms the period of increased mortality in early childhood and
highlights an excess mortality rate compared to the clinic-based patients, which
persists until early adulthood (Figure, regions A + C). This difference in mortality is
likely to be the result of follow-up from birth among cohort patients and has been
previously highlighted when examining the incidence of clinical events (1).Reference
(1)
Magnus SA, Hambleton IR, Moosdeen F, Serjeant GR. Recurrent infections in homozygous
sickle cell disease. Arch Dis Child 1999; 80(6):537-541. |
