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Antihistamine nasal sprays — Azelastine and olopatadine are available as prescription nasal sprays. These agents appear to have some antiinflammatory effect and can improve nasal congestion  They are similarly effective . Antihistamine nasal sprays have a rapid onset of action (less than 15 minutes) and can be administered "on demand" [9]. Azelastine has a bitter taste that can be bothersome to some patients, although this has been corrected in newer preparations [93. Azelastine can be sedating if it is inadvertently swallowed.