Yamanaka. (2007) Cell Stem Cell Vol 1, pp 39-49

Figure 2. Nanog-Mediated Enhancement of Reprogramming by Fusion with ES Cells

Nanog-overexpressing mouse ES cells showed a marked increase in reprogramming activity after fusion with neural stem (NS) cells. The forced expression of Nanog in NS cells was found to be less effective.

NANOG (pron. nanOg) is a transcription factor critically involved with self-renewal of undifferentiated embryonic stem cells. In humans, this protein is encoded by the NANOG gene.[1][2]