Figure 1.Examples of Genomic Imbalances Detected by a CMA but Not by G-Banded Karyotyping(A) A 10.9 Mb deletion, including more than 60 genes. The deletion includes the Williams-Beuren syndrome region at chromosome region 7q11 but extends beyond the typical breakpoints for this syndrome. The arrow is pointing to the deleted chromosome that was observed by retrospective analysis of G-banded slides. (B) A 7.2 Mb duplication on the long arm of chromosome 11. Again, the arrow is pointing to the chromosome that has the duplication shown by the darker G-positive band.