prev next front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |28 |29 |30 |31 |32 |33 |34 |35|36 |37 |38 |39 |40 |41 |42 |43 |44 |45 |46 |47 |48 |review

Percentage of Chromosomes Duplicated

 

 

Figure 4 Segmental duplications across the genome. a, Segmental duplications and

sequence gaps across the genome. Segmental duplications are indicated below the

chromosomes in blue (length $10 kb and sequence identity $95%). Large duplications

are shown to approximate scale; smaller ones are indicated as ticks. Sequence gaps are

indicated above the chromosomes in red. Large gaps (.300 kb) are shown to

approximate scale; smaller gaps are indicated as ticks with those that are 50 kb or smaller

shown as shorter ticks. Unfinished clones are indicated as black ticks. b, Percentage of

large segmental duplications by chromosome. This count includes both interchromosomal

and intrachromosomal duplications with length$1 kb and sequence identity$90%. The

blue bars show the result of direct analysis of near-complete sequence. The gold bars

show an independent estimate65 using whole-genome shotgun data to correct for

potential mis-assembly of such segmental duplications. The strong agreement suggests

that most segmental duplications are properly represented in near-complete genome

sequence. The discrepancy for chromosome X is probably a result of errors in the

independent estimate, due to limited coverage and diversity of data from this

chromosome15.