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In 2008, there were estimated 9.4 million new cases equivalents to 139 cases per 100,000 population of TB globally. In 2008, out of the estimated global annual incidence of 9.4 million TB cases, 1.98 million were estimated to have occurred in India, of whom 0.87 million were infectious cases, thus catering to a fifth of the global burden of TB. About 40% of Indian population is infected with TB bacillus. The incidence of TB in India is estimated based on findings of the nationwide annual risk of tuberculosis infection (ARTI) study conducted in 2000-2003. The national ARTI being 1.5%, the incidence on smear positive TB cases in the country is estimated as 75 new smear positive cases per 100,000 population