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Preeclampsia is a common complication of pregnancy, is associated with hyperlipidemia and insulin resistance, and is a predictor of future essential hypertension. Among young Colorado women, the risk of preeclampsia decreased with increasing gestational age in a dose-dependent fashion. Also, women born in the lowest weight category (under 4.5 lbs) were at greatest risk for preeclampsia (OR.= 5.2; 95% CI = 1.2-21.5) relative to women born at 8.5 lbs or more. However, in contrast to the Norwegian gestational diabetes data, there was no trend by birth weight categories.