Perception of need, medication effectiveness, and safety are all important patient-related factors for medication adherence.  As patients decide to fill their prescription, they take into account the necessity of treatment and the seriousness of their disease.15  Explaining the importance of the medication and how it will work to provide therapeutic benefit will facilitate adherence.  In addition, informing the patient/family of potential common side effects and what signs and symptoms to report will increase their sense of control and participation in the medication management process.21  Instructing the patients on the need to follow-up with prescribing providers, and facilitating securing such appointments, after initial treatment with new medications is important for establishing the effectiveness and safety of new medications and promotes medication adherence through several mechanisms.7