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The mean T1DM incidence was extremely higher in 2000-2006 study period: 16,0 cases per 100.000 children (95% CI 13,4-18,5) than in 1990-1999 and 1980-1989 study periods, where it was 8,5 (95% CI 7,1-9,9) and 5,4 (95% CI 4,1-6,6) accordingly.