In recent years, a number of studies have screened the entire human genome in families with more than one T1D individual to identify regions, other than the HLA region, that also contain T1D susceptibility genes.  The loci listed in this table represent a summary of the most likely candidate regions.  Although it is thought that many genes contribute to T1D susceptibility, we now know these genes all have a smaller influence on T1D compared to those in the HLA region.  As a result, the HLA region has been designated as IDDM1.