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100 puffs of 3 s duration spaced at 30-s intervals, the following results were obtained in a single smoking session: 2.25 mg nicotine, and relative to the smoke of a single cigarette, high levels of arsenic, cobalt, chromium, and lead .
 
 Charcoal used to burn tobacco produces additional toxins.
 

Second hand smoke threat from tobacco combustion and the fuel used to burn tobacco.

 
 Adding flavors makes it more appealing.