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A FCGH would represent an historical shift in global health, with a broadly imagined global governance regime. The initial framework would establish the key modalities, with a strategy for subsequent protocols on each of the most important governance parameters. It is not necessary, or perhaps even wise, to specify in detail the substance of an initial FCGH, but it may helpful to state the broad principles: FCGH mission—Convention Parties seek innovative solutions for the most pressing health problems facing the world in partnership with non-State actors and civil society, with particular emphasis on the most disadvantaged populations; FCGH objectives— establish fair terms of international cooperation, with agreed-upon mutually binding obligations to create enduring health system capacities, meet basic survival needs, and reduce global health disparities; Engagement and coordination—finding common purposes and process among a wide variety of State and non-State actors, setting priorities, and coordinating activities to achieve the mission of the FCGH; State Party, and other stakeholder obligations—incentives, forms of assistance (e.g., financial aid, debt relief, technical support, subsidies, tradable credits), and levels of assistance, with differentiated responsibility for developed, developing, and least developed countries; Institutional structures—conference of Parties, secretariat, technical advisory body, and financing mechanism, with integral involvement of non-State actors and civil society; Empirical monitoring—data gathering, benchmarks, and leading health indicators, such as maternal, infant, and child survival; Enforcement mechanisms—inducements, sanctions, mediation, and dispute resolution; Ongoing scientific analysis—processes for ongoing scientific research and evaluation on cost effective health interventions, such as the creation of an Intergovernmental Panel on Global Health, comprised of prominent medical and public health experts; and Guidance for subsequent law-making process—content, methods, and timetables to meet framework convention goals.