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What measures can you as a researcher take to minimize the risk of harm in the study? If you are to minimize harm, you first need to identify the types of harm possible  in  the groups of people involved.
Risks can be considered in the realm of physical, psychological and social.
 These can be identified in the context of the individual  compared to the community.
In research clinical eqipoise needs to be present.
What is clinical equipoise?