||Soon thereafter, Fred Li and I described a
series of families, some of which were seen in the Clinical Center, who were
prone to a wide variety of cancers, including sarcomas and breast cancer
occurring in children and young adults. The prevailing dogma at the time was
that familial cancer was site-specific, so the findings raised a lot of
eyebrows. As a result, Fred and I spent more time debating the title than
writing the text. But eventually Fred, being more conservative, won out and
we placed a question mark after “familial syndrome”.