prev next front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |28 |29 |30 |31 |32 |review
Next to be described was the Wilms tumor gene, WT1. The search for this tumor-suppressor gene was facilitated by a survey that Bob Miller and I carried out on Wilms tumor, which uncovered a pattern of malformations featuring congenital aniridia or absence of the iris. This tumor-malformation syndrome was subsequently linked to a chromosome deletion that helped others to localize and identify the Wilms tumor gene.