prev next front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |28 |29 |30 |review
The Kaplan-Meier method produces survival curves. To test the null hypothesis that two survival curves are identical, e.g. in a clinical trial with a control group (group A) and a treatment group (group B), the log rank test is commonly used. In the slide we use the subscript i to indicate "at time i", when a death is observed. The number of expected deaths in group A at time i (EAi) is equal to the number of at risk subjects in group A at time i divided by the total (groups A & B) number of at risk subjects at time i, multiplied by the total number of deaths at time i. EBi is calculated in the same way. Total expected deaths in group A and B (EA & EB) are then calculated by summing up the expected numbers at different times (i.e., sum EAi & sum EBi).