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Acknowledgements: My students who now occupy important chairs in the country and abroad worked hard, I am indebted to them- Drs Subhas Agarwal, Subhdra Sen, R M D Agarwal, V Gupta, R Devi, Arti Shukla, Chandrika Prasad, S K Upadhaya, K P Mishra, Deeksha Kapur deserve special mention. Prof (Mrs) Dev K Agarwal coordinator for the clinical studies gave strength.
 
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