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-Highly toxic (50 mg of nicotine can kill an adult if given intravenously) - Each cigarette contains between 3-8mg of nicotine Effects of Nicotine: -Addiction -Constriction in blood vessels (increase in blood pressure) -Platelet coagulation (blood clots) -Passes through the umbilical cord to fetus’s blood -Passes through breast milk http://www.nida.nih.gov/ResearchReports/Nicotine/nicotine2.html#what